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LOC127402582 H3K27ac hESC enhancer GRCh37_chr5:17218860-17219640 [ Homo sapiens (human) ]

Gene ID: 127402582, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127402582
Gene description
H3K27ac hESC enhancer GRCh37_chr5:17218860-17219640
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (17218751..17219531)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (17158129..17158910)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene BASP1 antisense RNA 1 Neighboring gene uncharacterized LOC105374664 Neighboring gene Sharpr-MPRA regulatory region 6771 Neighboring gene Sharpr-MPRA regulatory region 14227 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15948 Neighboring gene DDB1 and CUL4 associated factor 13 pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15949 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15950 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:17227689-17228189 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22424 Neighboring gene brain abundant membrane attached signal protein 1 Neighboring gene RNA, U6 small nuclear 1003, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15951 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:17275743-17276243 Neighboring gene BASP1-FTH1P10 intergenic CAGE-defined low expression enhancer Neighboring gene aurora kinase A interacting protein 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_104540.1 

    Range
    101..881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    17218751..17219531
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    17158129..17158910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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