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LOC127402577 NANOG hESC enhancer GRCh37_chr5:17066008-17066589 [ Homo sapiens (human) ]

Gene ID: 127402577, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127402577
Gene description
NANOG hESC enhancer GRCh37_chr5:17066008-17066589
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (17065899..17066480)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (17005240..17005821)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene myosin X Neighboring gene ribosomal protein S26 pseudogene 28 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:16951303-16951587 Neighboring gene RNA, U6 small nuclear 660, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:16994519-16995071 Neighboring gene uncharacterized LOC124900947 Neighboring gene Sharpr-MPRA regulatory region 7707 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17140500-17141038 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17141039-17141575 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:17145813-17146647 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17151192-17152159 Neighboring gene BASP1 antisense RNA 1 Neighboring gene microRNA 10522

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_104535.1 

    Range
    101..682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    17065899..17066480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    17005240..17005821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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