U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127270205 NANOG hESC enhancer GRCh37_chr1:147016860-147017378 [ Homo sapiens (human) ]

Gene ID: 127270205, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Gene symbol
LOC127270205
Gene description
NANOG hESC enhancer GRCh37_chr1:147016860-147017378
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (147545090..147545608)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (147262494..147263012, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 624 Neighboring gene olfactory receptor family 13 subfamily Z member 2 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr1:146958668-146958835 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1280 Neighboring gene olfactory receptor family 13 subfamily Z member 3 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:146974675-146975522 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:146975523-146976368 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:146976369-146977214 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:146981878-146982536 Neighboring gene MPRA-validated peak403 silencer Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:147012942-147013696 Neighboring gene BCL9 transcription coactivator Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:147067805-147068328 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1281 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1282 Neighboring gene uncharacterized LOC128071544 Neighboring gene Sharpr-MPRA regulatory region 10305 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:147091237-147092116 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:147092117-147092996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:147113153-147113654 Neighboring gene acid phosphatase 6, lysophosphatidic Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:147141494-147142437

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_092060.1 

    Range
    101..619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    147545090..147545608
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    147262494..147263012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases