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Cacnb3 calcium channel, voltage-dependent, beta 3 subunit [ Mus musculus (house mouse) ]

Gene ID: 12297, updated on 11-Apr-2024

Summary

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Official Symbol
Cacnb3provided by MGI
Official Full Name
calcium channel, voltage-dependent, beta 3 subunitprovided by MGI
Primary source
MGI:MGI:103307
See related
Ensembl:ENSMUSG00000003352 AllianceGenome:MGI:103307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CAB3; Beta3; Cchb3; Ca(v)beta3
Summary
Predicted to enable calcium channel regulator activity; high voltage-gated calcium channel activity; and protein kinase binding activity. Acts upstream of or within T cell receptor signaling pathway. Part of voltage-gated calcium channel complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human CACNB3 (calcium voltage-gated channel auxiliary subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in frontal lobe adult (RPKM 57.2), CNS E18 (RPKM 51.8) and 22 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 F1; 15 54.64 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98526317..98542410)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (98628436..98644536)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene cyclin T1 Neighboring gene RIKEN cDNA 9330020H09 gene Neighboring gene STARR-positive B cell enhancer ABC_E1917 Neighboring gene sperm microtubule inner protein 11 Neighboring gene adenylate cyclase 6 Neighboring gene STARR-seq mESC enhancer starr_39665 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:98440580-98440763 Neighboring gene STARR-positive B cell enhancer ABC_E9921 Neighboring gene STARR-seq mESC enhancer starr_39668 Neighboring gene DEAD box helicase 23 Neighboring gene STARR-positive B cell enhancer ABC_E8612 Neighboring gene STARR-positive B cell enhancer ABC_E9922 Neighboring gene Rho family GTPase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. IP(3) Receptor-Dependent Cytoplasmic Ca(2+) Signals Are Tightly Controlled by Cavβ3. Belkacemi A, et al. Cell Rep, 2018 Jan 30. PMID 29386119
  2. Absence of plateau potentials in dLGN cells leads to a breakdown in retinogeniculate refinement. Dilger EK, et al. J Neurosci, 2015 Feb 25. PMID 25716863, Free PMC Article
  3. Decreased calcium channel currents and facilitated epinephrine release in the Ca2+ channel beta3 subunit-null mice. Ohta T, et al. Biochem Biophys Res Commun, 2010 Apr 9. PMID 20144588
  4. Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels. Jha MK, et al. Nat Immunol, 2009 Dec. PMID 19838200, Free PMC Article
  5. Modified behavioral characteristics following ablation of the voltage-dependent calcium channel beta3 subunit. Murakami M, et al. Brain Res, 2007 Jul 30. PMID 17588550

See all (62) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. our results indicate that beta3, unrelated to its role as a Ca2+ channel subunit, specifically modulates the cell's IP3 sensitivity and thereby efficiently tunes agonist-induced cytoplasmic Ca2+ signals and cellular functions.
    Title: IP(3) Receptor-Dependent Cytoplasmic Ca(2+) Signals Are Tightly Controlled by Cavβ3.
  2. During development Cavbeta3 protein expression in the cerebellum peaks at postnatal days 15 and 21, and has diminished drastically by day 60, and in the hippocampus increases with age throughout all subfields.
    Title: Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.
  3. In transgenic mice lacking the calcium channel beta3 subunit, there are compensatory changes of calcium channel abundance leading to adaptation of alternate calcium transport mechanisms.
    Title: Impaired renal calcium absorption in mice lacking calcium channel beta 3 subunits.
  4. Differential gene expression analysis identifies murine Cacnb3 as strongly upregulated in distinct dendritic cell populations upon stimulation
    Title: Differential gene expression analysis identifies murine Cacnb3 as strongly upregulated in distinct dendritic cell populations upon stimulation.
  5. these results indicate the importance of the beta3 subunit in determining calcium channel characteristics and catecholamine release in adrenal chromaffin cells.
    Title: Decreased calcium channel currents and facilitated epinephrine release in the Ca2+ channel beta3 subunit-null mice.
  6. neither Ca(V)beta3 nor Ca(V)beta4 are indispensable for hair cell Ca(2+) currents but contribute to the overall current properties
    Title: Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4.
  7. Deficiency in beta3 regulatory subunit of voltage-gated calcium channels resulted in a profound survival defect of CD8(+) T cells.
    Title: Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.
  8. These results suggest a possibility that, unrelated to voltage-dependent Ca(2+) channels regulation, Ca(v)beta3 negatively regulates the NMDAR activity in the hippocampus.
    Title: Ablation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memory.
  9. Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel beta3 subunit.(
    Title: Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel beta3 subunit.
  10. Ca(V)beta(3) has only subtle effects on L-type Ca(2+) currents in ileum smooth muscle.
    Title: Ca2+ channel currents and contraction in CaVbeta3-deficient ileum smooth muscle from mouse.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium channel regulator activity ISO
Inferred from Sequence Orthology
more info
  
enables high voltage-gated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to high voltage-gated calcium channel activity ISO
Inferred from Sequence Orthology
more info
  
enables high voltage-gated calcium channel activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
contributes_to voltage-gated calcium channel activity ISO
Inferred from Sequence Orthology
more info
  
enables voltage-gated calcium channel activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within T cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in calcium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in calcium ion transmembrane transport via high voltage-gated calcium channel ISO
Inferred from Sequence Orthology
more info
  
involved_in calcium ion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
  
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of mechanical stimulus involved in sensory perception of pain ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of detection of mechanical stimulus involved in sensory perception of touch ISO
Inferred from Sequence Orthology
more info
  
involved_in neuromuscular junction development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of excitatory postsynaptic potential ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein targeting to membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of membrane hyperpolarization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of membrane repolarization during action potential ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of voltage-gated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of L-type voltage-gated calcium channel complex ISO
Inferred from Sequence Orthology
more info
  
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  
part_of monoatomic ion channel complex IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  
part_of voltage-gated calcium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of voltage-gated calcium channel complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of voltage-gated calcium channel complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit beta-3
Names
calcium channel voltage-dependent subunit beta 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044741.3 → NP_001038206.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC156543
    Consensus CDS
    CCDS37192.1
    UniProtKB/TrEMBL
    D3Z3Z3, Q8K5A7
    Related
    ENSMUSP00000104778.2, ENSMUST00000109150.9
    Conserved Domains (4) summary
    cd12042
    Location:57 → 124
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:175 → 355
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:15 → 57
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:185 → 356
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. NM_001286226.2 → NP_001273155.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC156543
    Consensus CDS
    CCDS88834.1
    UniProtKB/TrEMBL
    A0A2U3TZ49, Q8K5A7
    Related
    ENSMUSP00000003442.9, ENSMUST00000003442.9
    Conserved Domains (4) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:166 → 329
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:165 → 330
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  3. NM_001356543.2 → NP_001343472.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC156543
    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:57 → 124
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam12052
    Location:15 → 57
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl27059
    Location:174 → 354
    Guanylate_kin; Guanylate kinase

  4. NM_001410382.1 → NP_001397311.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC156543

  5. NM_001410383.1 → NP_001397312.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC156543

  6. NM_001410384.1 → NP_001397313.1  voltage-dependent L-type calcium channel subunit beta-3 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC156543

  7. NM_007581.4 → NP_031607.2  voltage-dependent L-type calcium channel subunit beta-3 isoform 1

    See identical proteins and their annotated locations for NP_031607.2

    Status: VALIDATED

    Source sequence(s)
    AC156543
    Consensus CDS
    CCDS27800.1
    UniProtKB/Swiss-Prot
    G5E821, P54285
    UniProtKB/TrEMBL
    Q8K5A7
    Related
    ENSMUSP00000155514.2, ENSMUST00000230490.2
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

RNA

  1. NR_177064.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC156543
    Related
    ENSMUST00000230064.2

  2. NR_177065.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC156543

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    98526317..98542410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017316418.3 → XP_017171907.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X10

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:45 → 112
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:163 → 343
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 45
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  2. XM_006520365.2 → XP_006520428.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X10

    See identical proteins and their annotated locations for XP_006520428.1

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:45 → 112
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:163 → 343
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 45
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  3. XM_036159101.1 → XP_036014994.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X12

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:45 → 112
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:163 → 343
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:3 → 45
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  4. XM_030248302.2 → XP_030104162.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  5. XM_030248304.2 → XP_030104164.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  6. XM_006520367.2 → XP_006520430.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X13

    See identical proteins and their annotated locations for XP_006520430.1

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  7. XM_017316415.3 → XP_017171904.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  8. XM_030248303.2 → XP_030104163.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  9. XM_036159097.1 → XP_036014990.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X5

    UniProtKB/Swiss-Prot
    G5E821, P54285
    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:176 → 356
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  10. XM_030248306.2 → XP_030104166.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X13

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  11. XM_036159102.1 → XP_036014995.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X13

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  12. XM_036159104.1 → XP_036014997.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X14

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  13. XM_036159100.1 → XP_036014993.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X11

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:49 → 116
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:167 → 347
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:7 → 49
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  14. XM_006520361.4 → XP_006520424.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X3

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:58 → 125
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:175 → 355
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:16 → 58
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  15. XM_006520363.4 → XP_006520426.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X6

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:52 → 119
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:170 → 350
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:10 → 52
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  16. XM_006520364.4 → XP_006520427.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X8

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:49 → 116
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:167 → 347
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:7 → 49
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  17. XM_036159106.1 → XP_036014999.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X15

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 111
    Guanylate_kin; Guanylate kinase

  18. XM_030248305.2 → XP_030104165.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X13

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  19. XM_036159103.1 → XP_036014996.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X14

    Conserved Domains (1) summary
    pfam00625
    Location:1 → 180
    Guanylate_kin; Guanylate kinase

  20. XM_036159099.1 → XP_036014992.1  voltage-dependent L-type calcium channel subunit beta-3 isoform X9

    UniProtKB/TrEMBL
    Q8K5A7
    Conserved Domains (3) summary
    cd12042
    Location:52 → 119
    SH3_CACNB3; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3
    pfam00625
    Location:170 → 350
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:10 → 52
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P54285.2 GenPept UniProtKB/Swiss-Prot:P54285

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