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Naa12 N(alpha)-acetyltransferase 12, NatA catalytic subunit [ Mus musculus (house mouse) ]

Gene ID: 117903916, updated on 8-Feb-2024

Summary

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Official Symbol
Naa12provided by MGI
Official Full Name
N(alpha)-acetyltransferase 12, NatA catalytic subunitprovided by MGI
Primary source
MGI:MGI:3833940
See related
Ensembl:ENSMUSG00000024571 AllianceGenome:MGI:3833940
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm16286
Summary
Predicted to enable peptide-glutamate-N-acetyltransferase activity and peptide-serine-N-acetyltransferase activity. Predicted to be involved in N-terminal peptidyl-glutamic acid acetylation and N-terminal peptidyl-serine acetylation. Predicted to be part of NatA complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
18 E3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (80250041..80255949)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (80206826..80212734)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene ribosome binding factor A, opposite strand Neighboring gene predicted gene, 46629 Neighboring gene STARR-positive B cell enhancer ABC_E5666 Neighboring gene ribosome binding factor A Neighboring gene thioredoxin-like 4A Neighboring gene heat shock factor binding protein 1-like 1 Neighboring gene solute carrier family 66 member 2 Neighboring gene STARR-seq mESC enhancer starr_45175

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway. Kweon HY, et al. Elife, 2021 Aug 6. PMID 34355692, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptide alpha-N-acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables peptide-glutamate-alpha-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptide-serine-alpha-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in N-terminal protein amino acid acetylation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NatA complex ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
N-alpha-acetyltransferase 11-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384178.1 → NP_001371107.1  N-alpha-acetyltransferase 11-like

    Status: VALIDATED

    Source sequence(s)
    AC131065
    UniProtKB/TrEMBL
    Q3TBP4, Q9CQX6
    Related
    ENSMUSP00000123193.2, ENSMUST00000125127.8
    Conserved Domains (1) summary
    COG0456
    Location:1 → 149
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    80250041..80255949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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