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Rims2 regulating synaptic membrane exocytosis 2 [ Mus musculus (house mouse) ]

Gene ID: 116838, updated on 21-Apr-2024

Summary

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Official Symbol
Rims2provided by MGI
Official Full Name
regulating synaptic membrane exocytosis 2provided by MGI
Primary source
MGI:MGI:2152972
See related
Ensembl:ENSMUSG00000037386 AllianceGenome:MGI:2152972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RIM2; Serg2; Rab3ip2; Syt3-rs; Rim2(+4A); mKIAA0751; Rim2(+40A); Rim2(+44A); 2810036I15Rik
Summary
Enables transmembrane transporter binding activity. A structural constituent of presynaptic active zone. Involved in neurotransmitter secretion; positive regulation of gene expression; and regulation of nervous system process. Acts upstream of or within several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of exocytosis; and signal release. Located in GABA-ergic synapse and inhibitory synapse. Is active in glutamatergic synapse. Is expressed in testis. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 7.7), cortex adult (RPKM 5.5) and 7 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 B3.1; 15 15.45 cM
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (39061681..39547768)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (39198286..39684372)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr15:38944202-38944502 Neighboring gene STARR-seq mESC enhancer starr_38473 Neighboring gene STARR-seq mESC enhancer starr_38474 Neighboring gene DDB1 and CUL4 associated factor 13 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_38478 Neighboring gene STARR-seq mESC enhancer starr_38479 Neighboring gene STARR-seq mESC enhancer starr_38480 Neighboring gene U6 snRNA-associated Sm-like protein LSm3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_38483 Neighboring gene STARR-seq mESC enhancer starr_38487 Neighboring gene STARR-seq mESC enhancer starr_38490 Neighboring gene STARR-seq mESC enhancer starr_38492 Neighboring gene dendrocyte expressed seven transmembrane protein Neighboring gene predicted gene 16291 Neighboring gene dihydropyrimidinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? Dulubova I, et al. EMBO J, 2005 Aug 17. PMID 16052212, Free PMC Article
  2. A presynaptic phosphosignaling hub for lasting homeostatic plasticity. Müller JA, et al. Cell Rep, 2022 Apr 19. PMID 35443170
  3. RIM C(2)B Domains Target Presynaptic Active Zone Functions to PIP(2)-Containing Membranes. de Jong APH, et al. Neuron, 2018 Apr 18. PMID 29606581, Free PMC Article
  4. Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses. Löhner M, et al. J Neurosci, 2017 Aug 16. PMID 28701482, Free PMC Article
  5. RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors. Grabner CP, et al. J Neurosci, 2015 Sep 23. PMID 26400943, Free PMC Article

See all (72) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice.
    Title: Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice.
  2. N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.
    Title: N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease.
  3. Here, the authors identify an essential role for the active zone protein RIM in stimulated somatodendritic dopamine release in the midbrain. In mice in which RIMs are selectively removed from dopamine neurons, action potentials failed to evoke significant somatodendritic release detected via D2 receptor-mediated currents.
    Title: RIM is essential for stimulated but not spontaneous somatodendritic dopamine release in the midbrain.
  4. RBPs perform unexpectedly broad roles at the active zone that together with those of RIMs are essential for all active zone functions.
    Title: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.
  5. Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha for the CaV2.1 variant containing the region encoded by exons 44 and 47.
    Title: C-terminal splice variants of P/Q-type Ca(2+) channel Ca(V)2.1 α(1) subunits are differentially regulated by Rab3-interacting molecule proteins.
  6. The function of RIM1/2 at rod ribbons is to enhance Cav1.4 channel activity, possibly through direct or indirect modulation of the channel.
    Title: RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.
  7. RIM2alpha and RIM2beta promote a large complement of synaptic CaV1.3 Ca(2+) channels at inner hair cell presynaptic active zones and are required for normal hearing.
    Title: Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.
  8. Experiments with single Rim 1/2 gene inactivation at the large calyx of Held synapse show largely overlapping roles of the two major Rim genes in vesicle priming/docking
    Title: RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse.
  9. Rim2alpha is involved in Zona Pellucida dependent signaling.
    Title: RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction.
  10. Data suggest that RIM1/2 proteins co-ordinately regulate key functions for fast transmitter release, enabling a high presynaptic Ca(2)+ channel density and vesicle docking at the active zone.
    Title: RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (6)  1 citation
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
  
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
enables protein-macromolecule adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein-macromolecule adaptor activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of presynaptic active zone IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of presynaptic active zone IEP
Inferred from Expression Pattern
more info
 PubMed 
enables structural constituent of presynaptic active zone IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium ion-regulated exocytosis of neurotransmitter IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within calcium ion-regulated exocytosis of neurotransmitter IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within calcium-ion regulated exocytosis IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in establishment of localization in cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within exocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within insulin secretion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in insulin secretion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within maintenance of presynaptic active zone structure IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within neurotransmitter secretion IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within neurotransmitter transport IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of dendrite extension ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of excitatory postsynaptic potential IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of gene expression IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of inhibitory postsynaptic potential IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of calcium-dependent activation of synaptic vesicle fusion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of calcium-dependent activation of synaptic vesicle fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of membrane potential IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of synaptic plasticity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of synaptic vesicle exocytosis ISO
Inferred from Sequence Orthology
more info
  
involved_in spontaneous neurotransmitter secretion IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in synaptic vesicle docking IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in synaptic vesicle docking IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptic vesicle priming IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in synaptic vesicle priming IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in GABA-ergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in GABA-ergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in cytoskeleton of presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in inhibitory synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in photoreceptor ribbon synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in presynaptic active zone cytoplasmic component ISO
Inferred from Sequence Orthology
more info
  
is_active_in presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
regulating synaptic membrane exocytosis protein 2
Names
RIM 2
Rab3 interacting protein 1
Rab3 interacting protein 2
rab-3-interacting protein 2
rab3-interacting protein 2
synaptic exocytosis regulator 2
synaptotagmin 3, related sequence

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256382.1 → NP_001243311.1  regulating synaptic membrane exocytosis protein 2 isoform a

    See identical proteins and their annotated locations for NP_001243311.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AC101886, AC101935, AC114537
    Consensus CDS
    CCDS56982.1
    UniProtKB/TrEMBL
    D9HP81, Q6ZQ55
    Related
    ENSMUSP00000048719.10, ENSMUST00000042917.10
    Conserved Domains (5) summary
    cd04028
    Location:1403 → 1548
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:774 → 900
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1001 → 1101
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:640 → 721
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:30 → 154
    PHD_SF; PHD finger superfamily

  2. NM_001256383.1 → NP_001243312.1  regulating synaptic membrane exocytosis protein 2 isoform b

    See identical proteins and their annotated locations for NP_001243312.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. It encodes isoform b which is shorter than isoform a.
    Source sequence(s)
    AC101886, AC101935, AC114537
    Consensus CDS
    CCDS88755.1
    UniProtKB/TrEMBL
    Q0VF51, Q6ZQ55
    Related
    ENSMUSP00000154153.2, ENSMUST00000227243.2
    Conserved Domains (4) summary
    cd04028
    Location:1381 → 1526
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:774 → 900
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:640 → 721
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:30 → 154
    PHD_SF; PHD finger superfamily

  3. NM_001256384.1 → NP_001243313.1  regulating synaptic membrane exocytosis protein 2 isoform d

    See identical proteins and their annotated locations for NP_001243313.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks most of the 5' exons, includes an alternate 5' terminal exon and maintains the reading frame, compared to variant 1. It encodes isoform d which is shorter than isoform a.
    Source sequence(s)
    AC114537, AK032619
    Consensus CDS
    CCDS88756.1
    UniProtKB/Swiss-Prot
    Q9EQZ7
    Related
    ENSMUSP00000153868.2, ENSMUST00000226410.2
    Conserved Domains (1) summary
    cd04028
    Location:116 → 261
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

  4. NM_053271.2 → NP_444501.1  regulating synaptic membrane exocytosis protein 2 isoform c

    See identical proteins and their annotated locations for NP_444501.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. It encodes isoform c which is shorter than isoform a.
    Source sequence(s)
    AB021131, AK032619, BY242489
    Consensus CDS
    CCDS37067.1
    UniProtKB/Swiss-Prot
    Q8C433, Q8CCK2, Q9EQZ7
    Related
    ENSMUSP00000080711.6, ENSMUST00000082054.12
    Conserved Domains (4) summary
    cd04028
    Location:1361 → 1506
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:814 → 940
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:680 → 761
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:30 → 194
    PHD_SF; PHD finger superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    39061681..39547768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017316372.2 → XP_017171861.1  regulating synaptic membrane exocytosis protein 2 isoform X4

    Conserved Domains (5) summary
    cd04028
    Location:1453 → 1598
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:780 → 903
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1013 → 1114
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:627 → 708
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  2. XM_036159081.1 → XP_036014974.1  regulating synaptic membrane exocytosis protein 2 isoform X12

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1417 → 1562
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:780 → 903
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1004 → 1104
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:627 → 708
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  3. XM_036159079.1 → XP_036014972.1  regulating synaptic membrane exocytosis protein 2 isoform X5

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1437 → 1582
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:761 → 887
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:997 → 1098
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:627 → 708
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  4. XM_017316375.2 → XP_017171864.1  regulating synaptic membrane exocytosis protein 2 isoform X9

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1428 → 1573
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:761 → 887
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:988 → 1089
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:627 → 708
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  5. XM_036159082.1 → XP_036014975.1  regulating synaptic membrane exocytosis protein 2 isoform X15

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1405 → 1550
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:761 → 887
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:627 → 708
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  6. XM_017316373.2 → XP_017171862.1  regulating synaptic membrane exocytosis protein 2 isoform X6

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1433 → 1578
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:760 → 883
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:993 → 1094
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:607 → 688
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  7. XM_017316374.2 → XP_017171863.1  regulating synaptic membrane exocytosis protein 2 isoform X7

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1432 → 1577
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:760 → 883
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:993 → 1093
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:607 → 688
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  8. XM_036159080.1 → XP_036014973.1  regulating synaptic membrane exocytosis protein 2 isoform X10

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1423 → 1568
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:760 → 883
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:984 → 1084
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:607 → 688
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  9. XM_030248287.1 → XP_030104147.1  regulating synaptic membrane exocytosis protein 2 isoform X13

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1417 → 1562
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:741 → 867
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:977 → 1078
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:607 → 688
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  10. XM_017316380.2 → XP_017171869.1  regulating synaptic membrane exocytosis protein 2 isoform X14

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1407 → 1552
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:741 → 867
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:968 → 1068
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:607 → 688
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  11. XM_017316370.2 → XP_017171859.1  regulating synaptic membrane exocytosis protein 2 isoform X1

    Conserved Domains (5) summary
    cd04028
    Location:1480 → 1625
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:807 → 930
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1040 → 1141
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:654 → 735
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  12. XM_017316371.2 → XP_017171860.1  regulating synaptic membrane exocytosis protein 2 isoform X3

    Conserved Domains (5) summary
    cd04028
    Location:1464 → 1609
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:788 → 914
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1024 → 1125
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:654 → 735
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl22851
    Location:118 → 168
    PHD_SF; PHD finger superfamily

  13. XM_030248286.1 → XP_030104146.1  regulating synaptic membrane exocytosis protein 2 isoform X8

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1429 → 1574
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:756 → 879
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:989 → 1090
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:603 → 684
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28890
    Location:118 → 162
    FYVE_like_SF; FYVE domain like superfamily

  14. XM_017316376.2 → XP_017171865.1  regulating synaptic membrane exocytosis protein 2 isoform X11

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1419 → 1564
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:756 → 879
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:980 → 1080
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:603 → 684
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28890
    Location:118 → 162
    FYVE_like_SF; FYVE domain like superfamily

  15. XM_030248285.1 → XP_030104145.1  regulating synaptic membrane exocytosis protein 2 isoform X2

    Conserved Domains (5) summary
    cd04028
    Location:1476 → 1621
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:803 → 926
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:1036 → 1137
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:650 → 731
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl28890
    Location:118 → 162
    FYVE_like_SF; FYVE domain like superfamily

  16. XM_017316385.3 → XP_017171874.1  regulating synaptic membrane exocytosis protein 2 isoform X19

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1247 → 1392
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:574 → 697
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:807 → 908
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:421 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  17. XM_017316401.3 → XP_017171890.1  regulating synaptic membrane exocytosis protein 2 isoform X33

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1028 → 1173
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:574 → 697
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:798 → 898
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:421 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  18. XM_017316403.3 → XP_017171892.1  regulating synaptic membrane exocytosis protein 2 isoform X35

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1021 → 1166
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:555 → 681
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:791 → 891
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:421 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  19. XM_036159089.1 → XP_036014982.1  regulating synaptic membrane exocytosis protein 2 isoform X40

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:999 → 1144
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:555 → 681
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:421 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  20. XM_017316405.3 → XP_017171894.1  regulating synaptic membrane exocytosis protein 2 isoform X37

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1012 → 1157
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:555 → 681
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:782 → 882
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:421 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  21. XM_017316387.3 → XP_017171876.1  regulating synaptic membrane exocytosis protein 2 isoform X20

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1227 → 1372
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:554 → 677
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:787 → 888
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  22. XM_030248298.2 → XP_030104158.1  regulating synaptic membrane exocytosis protein 2 isoform X43

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:987 → 1132
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:554 → 677
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:680 → 922
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  23. XM_036159088.1 → XP_036014981.1  regulating synaptic membrane exocytosis protein 2 isoform X38

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1008 → 1153
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:554 → 677
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:778 → 878
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  24. XM_017316410.3 → XP_017171899.1  regulating synaptic membrane exocytosis protein 2 isoform X44

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:986 → 1131
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:554 → 677
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:680 → 921
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  25. XM_030248300.2 → XP_030104160.1  regulating synaptic membrane exocytosis protein 2 isoform X48

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:926 → 1071
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:554 → 677
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  26. XM_017316389.3 → XP_017171878.1  regulating synaptic membrane exocytosis protein 2 isoform X21

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1211 → 1356
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:771 → 872
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  27. XM_030248292.2 → XP_030104152.1  regulating synaptic membrane exocytosis protein 2 isoform X22

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1210 → 1355
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:771 → 871
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  28. XM_017316407.3 → XP_017171896.1  regulating synaptic membrane exocytosis protein 2 isoform X39

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1001 → 1146
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:771 → 871
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  29. XM_036159085.1 → XP_036014978.1  regulating synaptic membrane exocytosis protein 2 isoform X25

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:1188 → 1333
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  30. XM_036159090.1 → XP_036014983.1  regulating synaptic membrane exocytosis protein 2 isoform X45

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:979 → 1124
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  31. XM_030248293.2 → XP_030104153.1  regulating synaptic membrane exocytosis protein 2 isoform X23

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1202 → 1347
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:762 → 863
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  32. XM_017316409.3 → XP_017171898.1  regulating synaptic membrane exocytosis protein 2 isoform X41

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    TIGR00934
    Location:659 → 934
    2a38euk; potassium uptake protein, Trk family
    cd04028
    Location:993 → 1138
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:762 → 863
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  33. XM_030248296.2 → XP_030104156.1  regulating synaptic membrane exocytosis protein 2 isoform X28

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1154 → 1299
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:664 → 896
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  34. XM_030248299.2 → XP_030104159.1  regulating synaptic membrane exocytosis protein 2 isoform X46

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:971 → 1116
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:664 → 906
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  35. XM_030248301.2 → XP_030104161.1  regulating synaptic membrane exocytosis protein 2 isoform X49

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:911 → 1056
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  36. XM_030248294.2 → XP_030104154.1  regulating synaptic membrane exocytosis protein 2 isoform X24

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1190 → 1335
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:730 → 935
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  37. XM_017316397.3 → XP_017171886.1  regulating synaptic membrane exocytosis protein 2 isoform X27

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1164 → 1309
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:730 → 935
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  38. XM_006520343.5 → XP_006520406.1  regulating synaptic membrane exocytosis protein 2 isoform X42

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:992 → 1137
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:762 → 862
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  39. XM_030248295.2 → XP_030104155.1  regulating synaptic membrane exocytosis protein 2 isoform X26

    UniProtKB/TrEMBL
    Q6ZQ55
    Related
    ENSMUSP00000154531.2, ENSMUST00000227381.2
    Conserved Domains (3) summary
    cd04028
    Location:1179 → 1324
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  40. XM_036159086.1 → XP_036014979.1  regulating synaptic membrane exocytosis protein 2 isoform X29

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1142 → 1287
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:664 → 904
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  41. XM_017316412.3 → XP_017171901.1  regulating synaptic membrane exocytosis protein 2 isoform X47

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:970 → 1115
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:535 → 661
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:664 → 905
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:401 → 482
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  42. XM_036159083.1 → XP_036014976.1  regulating synaptic membrane exocytosis protein 2 isoform X16

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1274 → 1419
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:601 → 724
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:834 → 935
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  43. XM_017316399.3 → XP_017171888.1  regulating synaptic membrane exocytosis protein 2 isoform X30

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1064 → 1209
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:601 → 724
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:834 → 934
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  44. XM_036159084.1 → XP_036014977.1  regulating synaptic membrane exocytosis protein 2 isoform X17

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1258 → 1403
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:818 → 919
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  45. XM_017316400.3 → XP_017171889.1  regulating synaptic membrane exocytosis protein 2 isoform X31

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    cd04028
    Location:1048 → 1193
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:818 → 918
    PHA02666; hypothetical protein; Provisional
    PHA03307
    Location:786 → 997
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  46. XM_036159087.1 → XP_036014980.1  regulating synaptic membrane exocytosis protein 2 isoform X34

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (3) summary
    cd04028
    Location:1026 → 1171
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  47. XM_030248297.2 → XP_030104157.1  regulating synaptic membrane exocytosis protein 2 isoform X32

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (5) summary
    TIGR00934
    Location:706 → 981
    2a38euk; potassium uptake protein, Trk family
    cd04028
    Location:1040 → 1185
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:809 → 910
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  48. XM_017316404.3 → XP_017171893.1  regulating synaptic membrane exocytosis protein 2 isoform X36

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1018 → 1163
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03307
    Location:711 → 953
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  49. XM_017316384.3 → XP_017171873.1  regulating synaptic membrane exocytosis protein 2 isoform X18

    UniProtKB/TrEMBL
    Q6ZQ55
    Conserved Domains (4) summary
    cd04028
    Location:1248 → 1393
    C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
    cd04031
    Location:582 → 708
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA02666
    Location:809 → 909
    PHA02666; hypothetical protein; Provisional
    cd00992
    Location:448 → 529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9EQZ7.1 GenPept UniProtKB/Swiss-Prot:Q9EQZ7

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