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Crybg1 crystallin beta-gamma domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 11630, updated on 21-Apr-2024

Summary

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Official Symbol
Crybg1provided by MGI
Official Full Name
crystallin beta-gamma domain containing 1provided by MGI
Primary source
MGI:MGI:109544
See related
Ensembl:ENSMUSG00000019866 AllianceGenome:MGI:109544
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Aim1
Summary
Is expressed in several structures, including genitourinary system; heart; lung; skeletal musculature; and skin. Orthologous to human CRYBG1 (crystallin beta-gamma domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in large intestine adult (RPKM 7.7), bladder adult (RPKM 6.7) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B2; 10 23.14 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (43826303..44024824, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (43950307..44148828, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26525 Neighboring gene STARR-seq mESC enhancer starr_26526 Neighboring gene glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 Neighboring gene STARR-seq mESC enhancer starr_26527 Neighboring gene STARR-positive B cell enhancer ABC_E6838 Neighboring gene reticulon 4 interacting protein 1 Neighboring gene STARR-seq mESC enhancer starr_26529 Neighboring gene STARR-seq mESC enhancer starr_26530 Neighboring gene predicted gene, 40636 Neighboring gene STARR-seq mESC enhancer starr_26531 Neighboring gene STARR-seq mESC enhancer starr_26532 Neighboring gene STARR-seq mESC enhancer starr_26533 Neighboring gene preferentially expressed antigen in melanoma like 7 pseudogene Neighboring gene coiled-coil domain containing 137 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cloning and tissue expression of the mouse ortholog of AIM1, a betagamma-crystallin superfamily member. Teichmann U, et al. Mamm Genome, 1998 Sep. PMID 9716656
  2. Physical and transcriptional map of the mouse Chromosome 10 proximal region syntenic to human 6q16-q21. Chalhoub N, et al. Mamm Genome, 2001 Dec. PMID 11707774
  3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
beta/gamma crystallin domain-containing protein 1
Names
absent in melanoma 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368305.1 → NP_001355234.1  beta/gamma crystallin domain-containing protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC153534, AC153863, AC158637
    Consensus CDS
    CCDS88000.1
    UniProtKB/TrEMBL
    A0A0G2JG52
    Related
    ENSMUSP00000143429.2, ENSMUST00000200401.2
    Conserved Domains (5) summary
    PHA03247
    Location:445 → 1089
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:258 → 514
    PRK07003; DNA polymerase III subunit gamma/tau
    PRK07764
    Location:141 → 334
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00161
    Location:1933 → 2061
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00030
    Location:1563 → 1656
    Crystall; Beta/Gamma crystallin

  2. NM_001368306.1 → NP_001355235.1  beta/gamma crystallin domain-containing protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153534, AC158637
    Conserved Domains (5) summary
    PHA03247
    Location:346 → 990
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:156 → 415
    PRK07003; DNA polymerase III subunit gamma/tau
    PRK07764
    Location:42 → 235
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00161
    Location:1834 → 1962
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00030
    Location:1464 → 1557
    Crystall; Beta/Gamma crystallin

  3. NM_172393.2 → NP_765981.2  beta/gamma crystallin domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153534, AC158637, AK041082
    Consensus CDS
    CCDS48553.1
    UniProtKB/TrEMBL
    E9PVP1
    Related
    ENSMUSP00000020017.9, ENSMUST00000020017.14
    Conserved Domains (3) summary
    PHA03247
    Location:22 → 715
    PHA03247; large tegument protein UL36; Provisional
    cd00161
    Location:1559 → 1687
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00030
    Location:1189 → 1282
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    43826303..44024824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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