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LINC02574 long intergenic non-protein coding RNA 2574 [ Homo sapiens (human) ]

Gene ID: 111216282, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02574provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2574provided by HGNC
Primary source
HGNC:HGNC:53746
See related
Ensembl:ENSG00000233975 AllianceGenome:HGNC:53746
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HEAL
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Genomic context

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Location:
1p35.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (27660328..27662722, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (27501639..27504030, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (27986839..27989233, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:27939571-27940071 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:27941009-27941556 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 525 Neighboring gene FGR proto-oncogene, Src family tyrosine kinase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:27950023-27950844 Neighboring gene Sharpr-MPRA regulatory region 6936 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:27958413-27958913 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 563 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 526 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 564 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 565 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:27977663-27978629 Neighboring gene uncharacterized LOC729973 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:27981022-27981424 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:27985747-27986247 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 527 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:27988849-27989364 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:27989365-27989880 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 567 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 568 Neighboring gene interferon alpha inducible protein 6 Neighboring gene RNA, U6 small nuclear 949, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. Chao TC, et al. mBio, 2019 Sep 24. PMID 31551335, Free PMC Article
  2. Epidermal long non-coding RNAs are regulated by ultraviolet irradiation. Kim KH, et al. Gene, 2017 Dec 30. PMID 28942040

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Genotypes

General gene information

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Other Names

  • HIV-1-enhanced lncRNA
  • RP11-288L9.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_151722.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL445490
    Related
    ENST00000440492.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    27660328..27662722 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    27501639..27504030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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