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Iglc3 immunoglobulin lambda constant 3 [ Mus musculus (house mouse) ]

Gene ID: 110787, updated on 8-Feb-2024

Summary

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Official Symbol
Iglc3provided by MGI
Official Full Name
immunoglobulin lambda constant 3provided by MGI
Primary source
MGI:MGI:99886
See related
Ensembl:ENSMUSG00000105547 IMGT/GENE-DB:IGLC3; AllianceGenome:MGI:99886
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Igl-C3; 2010309G21Rik
Summary
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
16 A3; 16 11.81 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (18884115..18884431, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (19065365..19065681, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda chain complex Neighboring gene immunoglobulin lambda constant 1 Neighboring gene immunoglobulin lambda joining 1 Neighboring gene immunoglobulin lambda joining 3 pseudogene Neighboring gene immunoglobulin lambda joining 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a third type of lambda light chain in mouse immunoglobulins. Azuma T, et al. Proc Natl Acad Sci U S A, 1981 Jan. PMID 6165998, Free PMC Article
  2. Physical linkage of the constant region genes for immunoglobulins lambda I and lambda III. Miller J, et al. Proc Natl Acad Sci U S A, 1981 Jun. PMID 6267606, Free PMC Article
  3. Evolution of mouse immunoglobulin lambda genes. Selsing E, et al. Proc Natl Acad Sci U S A, 1982 Aug. PMID 6812053, Free PMC Article
  4. Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Kurey I, et al. Immunogenetics, 2009 Sep. PMID 19705113, Free PMC Article
  5. IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Giudicelli V, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608191, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Other Names

  • immunoglobulin lambda chain, constant region 3

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in immunoglobulin mediated immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of IgG immunoglobulin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_004051.1 

    Range
    195664..195980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    18884115..18884431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P01845.1 GenPept UniProtKB/Swiss-Prot:P01845

Gene LinkOut

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