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Iglv2 immunoglobulin lambda variable 2 [ Mus musculus (house mouse) ]

Gene ID: 110612, updated on 8-Feb-2024

Summary

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Official Symbol
Iglv2provided by MGI
Official Full Name
immunoglobulin lambda variable 2provided by MGI
Primary source
MGI:MGI:99548
See related
Ensembl:ENSMUSG00000076940 IMGT/GENE-DB:IGLV2; AllianceGenome:MGI:99548
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Igl-V2
Summary
Predicted to act upstream of or within adaptive immune response. Predicted to be part of immunoglobulin complex. Orthologous to several human genes including IGLV7-43 (immunoglobulin lambda variable 7-43). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
16 A3; 16 11.93 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (19079153..19079594, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (19260403..19260844, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda chain complex Neighboring gene immunoglobulin lambda joining 2 Neighboring gene predicted gene, 35545 Neighboring gene STARR-positive B cell enhancer mm9_chr16:19246220-19246520 Neighboring gene STARR-positive B cell enhancer ABC_E8622 Neighboring gene immunoglobulin lambda variable 3 Neighboring gene olfactory receptor family 2 subfamily M member 12 Neighboring gene predicted gene, 22158

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Preparation of a semisynthetic antibody. Gavish M, et al. Biochemistry, 1978 Apr 4. PMID 418802
  2. Organization of immunoglobulin genes. Tonegawa S, et al. Cold Spring Harb Symp Quant Biol, 1978. PMID 98276
  3. Amino acid sequence of the light chain of a mouse myeloma protein (MOPC-315). Dugan ES, et al. Biochemistry, 1973 Dec 18. PMID 4760498
  4. The anti-DNA-associated idiotype 8.12 is encoded by the V lambda II gene family and maps to the vicinity of L chain CDR1. Paul E, et al. J Immunol, 1992 Dec 1. PMID 1431128
  5. Structure and function of immunoglobulin genes and precursors. Schechter I, et al. Fed Proc, 1979 Apr. PMID 428562

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • immunoglobulin lambda chain, variable 2
  • immunoglobulin lambda-2
  • light chain variable region

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of immunoglobulin complex IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_004051.1 

    Range
    501..942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    19079153..19079594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P01728.1 GenPept UniProtKB/Swiss-Prot:P01728

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases