U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pigh phosphatidylinositol glycan anchor biosynthesis, class H [ Mus musculus (house mouse) ]

Gene ID: 110417, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Pighprovided by MGI
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class Hprovided by MGI
Primary source
MGI:MGI:99463
See related
Ensembl:ENSMUSG00000021120 AllianceGenome:MGI:99463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PIG-H; 2210416H01Rik; A930028P05Rik
Summary
Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and respiratory system. Orthologous to human PIGH (phosphatidylinositol glycan anchor biosynthesis class H). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 13.4), placenta adult (RPKM 9.3) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
12 C3; 12 35.51 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (79127443..79136478, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (79080669..79089753, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_32582 Neighboring gene transmembrane protein 229B Neighboring gene STARR-seq mESC enhancer starr_32583 Neighboring gene STARR-seq mESC enhancer starr_32585 Neighboring gene STARR-seq mESC enhancer starr_32589 Neighboring gene pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 Neighboring gene predicted gene, 53729 Neighboring gene RIKEN cDNA 9230116L04 gene Neighboring gene STARR-positive B cell enhancer ABC_E10760 Neighboring gene STARR-seq mESC enhancer starr_32591 Neighboring gene ribosomal protein large PO subunit pseudogene Neighboring gene arginase type II Neighboring gene predicted gene, 40462

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Chromosomal assignment of genes involved in glycosylphosphatidylinositol anchor biosynthesis: implications for the pathogenesis of paroxysmal nocturnal hemoglobinuria. Ware RE, et al. Blood, 1994 Jun 15. PMID 8204896
  2. Chromosomal mapping of Adam9, Adam15 and Adam21. Seldin MF, et al. Matrix Biol, 2000 May. PMID 10842103
  3. Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains. Wergedal JE, et al. J Lipid Res, 2007 Aug. PMID 17496333
  4. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
  5. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC102258

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
phosphatidylinositol N-acetylglucosaminyltransferase subunit H
Names
phosphatidylinositol glycan, class H
phosphatidylinositol-glycan biosynthesis class H protein
NP_084264.1
XP_030102381.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001428964.1 → NP_001415893.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165249

  2. NM_029988.3 → NP_084264.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform 1

    See identical proteins and their annotated locations for NP_084264.1

    Status: VALIDATED

    Source sequence(s)
    AC165249
    Consensus CDS
    CCDS26006.1
    UniProtKB/Swiss-Prot
    Q5M9N4
    UniProtKB/TrEMBL
    Q8BMJ9
    Related
    ENSMUSP00000072018.8, ENSMUST00000072154.9
    Conserved Domains (1) summary
    pfam10181
    Location:90 → 158
    PIG-H; GPI-GlcNAc transferase complex, PIG-H component

RNA

  1. NR_190557.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC165249

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    79127443..79136478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246521.2 → XP_030102381.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1

    Conserved Domains (1) summary
    pfam10181
    Location:27 → 96
    PIG-H; GPI-GlcNAc transferase complex, PIG-H component
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5M9N4.1 GenPept UniProtKB/Swiss-Prot:Q5M9N4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous