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Amy2a5 amylase 2a5 [ Mus musculus (house mouse) ]

Gene ID: 109959, updated on 9-Dec-2024

Summary

Official Symbol
Amy2a5provided by MGI
Official Full Name
amylase 2a5provided by MGI
Primary source
MGI:MGI:88020
See related
Ensembl:ENSMUSG00000074268 AllianceGenome:MGI:88020
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Amy2; Amy-2; mAmy2-2; 1810008N23Rik
Summary
Enables amylase activity. Predicted to be involved in carbohydrate catabolic process. Located in extracellular space. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to several human genes including AMY2A (amylase alpha 2A) and AMY2B (amylase alpha 2B). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in spleen adult (RPKM 1235.2), small intestine adult (RPKM 952.2) and 2 other tissues See more
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Genomic context

See Amy2a5 in Genome Data Viewer
Location:
3 F3; 3 49.35 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (113156494..113166015, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (113249178..113258699, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene amylase 2b Neighboring gene amylase 2, pseudogene 1 Neighboring gene amylase 2a4 Neighboring gene amylase 2a3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC107496, MGC118682

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables alpha-amylase activity  
enables alpha-amylase activity  
enables alpha-amylase activity  
enables amylase activity PubMed 
enables calcium ion binding  
enables calcium ion binding  
enables chloride ion binding  
enables chloride ion binding  
Process Evidence Code Pubs
involved_in carbohydrate catabolic process  
involved_in carbohydrate metabolic process  
Component Evidence Code Pubs
is_active_in extracellular space  
located_in extracellular space PubMed 
located_in extracellular space  
located_in extracellular space  

General protein information

Preferred Names
pancreatic alpha-amylase 2a5
Names
1,4-alpha-D-glucan glucanohydrolase
PA
amylase 2, pancreatic
amylase 2a5, pancreatic
pancreatic alpha-amylase
NP_001036176.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042711.2NP_001036176.1  pancreatic alpha-amylase 2a5 precursor

    See identical proteins and their annotated locations for NP_001036176.1

    Status: PROVISIONAL

    Source sequence(s)
    AK133526
    Consensus CDS
    CCDS17775.1
    UniProtKB/Swiss-Prot
    P00688, Q4VBW6, Q61295, Q61296, Q64301
    Related
    ENSMUSP00000096270.4, ENSMUST00000098673.5
    Conserved Domains (3) summary
    cd11317
    Location:25413
    AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
    smart00632
    Location:420507
    Aamy_C; Aamy_C domain
    COG0366
    Location:46344
    AmyA; Glycosidase [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    113156494..113166015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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