U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ank2 ankyrin 2, brain [ Mus musculus (house mouse) ]

Gene ID: 109676, updated on 21-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Ank2provided by MGI
Official Full Name
ankyrin 2, brainprovided by MGI
Primary source
MGI:MGI:88025
See related
Ensembl:ENSMUSG00000032826 AllianceGenome:MGI:88025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ank-2; Gm4392; 100043364
Summary
Enables several functions, including ATPase binding activity; potassium channel regulator activity; and transmembrane transporter binding activity. Involved in several processes, including positive regulation of ion transmembrane transporter activity; regulation of cardiac muscle cell action potential; and regulation of heart contraction. Acts upstream of or within several processes, including cardiac muscle contraction; regulation of cardiac muscle cell membrane potential; and regulation of cation channel activity. Located in several cellular components, including T-tubule; intercalated disc; and myofibril. Is integral component of plasma membrane. Is active in paranodal junction. Is expressed in central nervous system; eye; genitourinary system; and heart. Used to study sinoatrial node disease. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 17.1), frontal lobe adult (RPKM 13.9) and 9 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
3 G2; 3 56.07 cM
Exon count:
63
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (126715256..127293996, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (126921607..127500347, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_08934 Neighboring gene STARR-seq mESC enhancer starr_08935 Neighboring gene predicted gene, 46823 Neighboring gene STARR-positive B cell enhancer mm9_chr3:126278818-126279119 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:126299066-126299249 Neighboring gene STARR-positive B cell enhancer ABC_E7941 Neighboring gene STARR-positive B cell enhancer ABC_E9570 Neighboring gene STARR-positive B cell enhancer ABC_E8805 Neighboring gene calcium/calmodulin-dependent protein kinase II, delta Neighboring gene STARR-positive B cell enhancer mm9_chr3:126393622-126393923 Neighboring gene STARR-positive B cell enhancer ABC_E9571 Neighboring gene VISTA enhancer mm1653 Neighboring gene predicted gene 15551 Neighboring gene STARR-positive B cell enhancer mm9_chr3:126454256-126454557 Neighboring gene STARR-positive B cell enhancer ABC_E11215 Neighboring gene STARR-positive B cell enhancer mm9_chr3:126474504-126474805 Neighboring gene STARR-positive B cell enhancer ABC_E11216 Neighboring gene STARR-seq mESC enhancer starr_08938 Neighboring gene STARR-seq mESC enhancer starr_08939 Neighboring gene STARR-positive B cell enhancer mm9_chr3:126606343-126606644 Neighboring gene STARR-seq mESC enhancer starr_08940 Neighboring gene STARR-seq mESC enhancer starr_08941 Neighboring gene predicted gene, 25501 Neighboring gene STARR-seq mESC enhancer starr_08943 Neighboring gene RIKEN cDNA C230031I18 gene Neighboring gene predicted gene, 16958 Neighboring gene STARR-seq mESC enhancer starr_08946 Neighboring gene STARR-seq mESC enhancer starr_08947 Neighboring gene STARR-positive B cell enhancer mm9_chr3:127025925-127026226 Neighboring gene STARR-seq mESC enhancer starr_08948 Neighboring gene STARR-seq mESC enhancer starr_08950 Neighboring gene predicted gene, 52631 Neighboring gene predicted gene, 35535 Neighboring gene predicted gene, 51018 Neighboring gene microRNA 302b Neighboring gene microRNA 302c Neighboring gene La ribonucleoprotein 7, transcriptional regulator

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant. Wallace MJ, et al. J Biol Chem, 2023 Jun. PMID 37182735, Free PMC Article
  2. Autism-associated ANK2 regulates embryonic neurodevelopment. Kawano S, et al. Biochem Biophys Res Commun, 2022 May 21. PMID 35313230
  3. Brain-wide electrical dynamics encode individual appetitive social behavior. Mague SD, et al. Neuron, 2022 May 18. PMID 35294900, Free PMC Article
  4. Elevated local [Ca2+] and CaMKII promote spontaneous Ca2+ release in ankyrin-B-deficient hearts. Popescu I, et al. Cardiovasc Res, 2016 Aug 1. PMID 27131508, Free PMC Article
  5. I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation. Stokke MK, et al. Cardiovasc Res, 2013 May 1. PMID 23417043

See all (108) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites.
    Title: Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites.
  2. Ankyrin B promotes developmental spine regulation in the mouse prefrontal cortex.
    Title: Ankyrin B promotes developmental spine regulation in the mouse prefrontal cortex.
  3. Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome.
    Title: Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome.
  4. Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant.
    Title: Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant.
  5. Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.
    Title: Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.
  6. Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.
    Title: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.
  7. Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes.
    Title: Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes.
  8. These novel findings have important implications for understanding the role of AnkB and Cav2.1 in the regulation of neuronal function in health and disease.
    Title: Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels.
  9. findings introduce what we believe to be a new pathway for Arrhythmogenic cardiomyopathy, a role of ankyrin-B in cardiac structure and signaling, a molecular link between ankyrin-B and beta-catenin, and evidence for targeted activation of the WNT/beta-catenin pathway as a potential treatment for this disease.
    Title: Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
  10. Gain of axon branching due to giant ankB deficiency/mutation is a candidate cellular mechanism to explain aberrant structural connectivity and penetrant behavioral consequences in mice as well as humans bearing autism spectrum disorder-related ANK2 mutations.
    Title: ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity.
Submit: New GeneRIF Correction See all GeneRIFs (35)

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables phosphorylation-dependent protein binding ISO
Inferred from Sequence Orthology
more info
  
enables potassium channel regulator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables protein-macromolecule adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein-macromolecule adaptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables spectrin binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
enables transmembrane transporter binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transmembrane transporter binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in SA node cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in SA node cell to atrial cardiac muscle cell communication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in SA node cell to atrial cardiac muscle cell communication ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within T-tubule organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in T-tubule organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in atrial cardiac muscle cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in atrial cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
  
involved_in atrial cardiac muscle cell to AV node cell communication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in atrial septum development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cardiac muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of calcium ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of calcium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of cation channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of potassium ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to M-band IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to T-tubule IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to T-tubule IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to cell surface IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to organelle ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within protein localization to plasma membrane IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of AV node cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of SA node cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of SA node cell action potential ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of apoptotic process RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
involved_in regulation of atrial cardiac muscle cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of atrial cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of calcium ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of calcium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of calcium ion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cardiac muscle cell contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cardiac muscle cell contraction ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of cardiac muscle cell membrane potential IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of cardiac muscle cell membrane potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cardiac muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of cardiac muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cardiac muscle contraction ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cardiac muscle contraction by calcium ion signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cardiac muscle contraction by calcium ion signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IC
Inferred by Curator
more info
 PubMed 
involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of cation channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of heart rate IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of heart rate ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of heart rate by cardiac conduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of heart rate by cardiac conduction ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein stability IC
Inferred by Curator
more info
 PubMed 
involved_in regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of ventricular cardiac muscle cell membrane repolarization ISO
Inferred from Sequence Orthology
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in ventricular cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in A band IDA
Inferred from Direct Assay
more info
 PubMed 
located_in M band IDA
Inferred from Direct Assay
more info
 PubMed 
located_in M band IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in T-tubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in T-tubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Z disc IDA
Inferred from Direct Assay
more info
 PubMed 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in costamere IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in extrinsic component of cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in intercalated disc IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
is_active_in paranodal junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
located_in sarcolemma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in sarcolemma IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ankyrin-2
Names
ankyrin-B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034168.1 → NP_001029340.1  ankyrin-2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK083826, BC043123, BP753425
    UniProtKB/Swiss-Prot
    Q8C8R3
    Conserved Domains (1) summary
    cd08804
    Location:494 → 577
    Death_ank2; Death domain of Ankyrin-2

  2. NM_001327938.1 → NP_001314867.1  ankyrin-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC102480, AC102591, AC113952, BP753425
    Conserved Domains (8) summary
    smart00218
    Location:961 → 1098
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00248
    Location:525 → 550
    ANK; ankyrin repeats
    COG0666
    Location:302 → 500
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:223 → 348
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08804
    Location:3543 → 3626
    Death_ank2; Death domain of Ankyrin-2
    pfam12796
    Location:233 → 324
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:33 → 80
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:426 → 457
    ANK; ANK repeat [structural motif]

  3. NM_001327939.1 → NP_001314868.1  ankyrin-2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC102480, AC102591, AC105163, BP753425
    Consensus CDS
    CCDS84672.1
    UniProtKB/TrEMBL
    S4R2R5
    Related
    ENSMUSP00000138753.4, ENSMUST00000182078.9
    Conserved Domains (8) summary
    smart00218
    Location:912 → 1016
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    smart00248
    Location:574 → 602
    ANK; ankyrin repeats
    COG0666
    Location:285 → 483
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:206 → 331
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08804
    Location:3461 → 3544
    Death_ank2; Death domain of Ankyrin-2
    pfam12796
    Location:216 → 307
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:16 → 63
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]

  4. NM_178655.3 → NP_848770.2  ankyrin-2 isoform 2

    See identical proteins and their annotated locations for NP_848770.2

    Status: VALIDATED

    Source sequence(s)
    AK032060, BC043123, BC059251, BP753425
    Consensus CDS
    CCDS38625.1
    UniProtKB/Swiss-Prot
    Q8C8R3
    Related
    ENSMUSP00000043765.8, ENSMUST00000044443.15
    Conserved Domains (2) summary
    smart00218
    Location:128 → 232
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    cd08804
    Location:611 → 694
    Death_ank2; Death domain of Ankyrin-2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    126715256..127293996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162834.1 → XP_036018727.1  ankyrin-2 isoform X25

    Conserved Domains (10) summary
    smart00218
    Location:996 → 1133
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2244 → 2651
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:392 → 677
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3193 → 3520
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2741 → 2972
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3578 → 3661
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:418 → 449
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:749 → 801
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1354 → 1483
    UPA_2; UPA domain
    cl39094
    Location:549 → 773
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_036162844.1 → XP_036018737.1  ankyrin-2 isoform X37

    Conserved Domains (11) summary
    smart00218
    Location:971 → 1108
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2219 → 2626
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:25 → 333
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3168 → 3495
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2716 → 2947
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3553 → 3636
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:426 → 457
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:724 → 776
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1329 → 1458
    UPA_2; UPA domain
    pfam12796
    Location:398 → 489
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:473 → 748
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_006500891.3 → XP_006500954.1  ankyrin-2 isoform X28

    Conserved Domains (10) summary
    smart00218
    Location:986 → 1123
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2234 → 2641
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:400 → 685
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3183 → 3510
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2731 → 2962
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3568 → 3651
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:426 → 457
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:757 → 809
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1344 → 1473
    UPA_2; UPA domain
    cl39094
    Location:557 → 781
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_036162832.1 → XP_036018725.1  ankyrin-2 isoform X21

    Conserved Domains (10) summary
    smart00218
    Location:1004 → 1141
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2252 → 2659
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:400 → 685
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3201 → 3528
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2749 → 2980
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3586 → 3669
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:426 → 457
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:757 → 809
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1362 → 1491
    UPA_2; UPA domain
    cl39094
    Location:557 → 781
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_036162820.1 → XP_036018713.1  ankyrin-2 isoform X9

    Conserved Domains (10) summary
    smart00218
    Location:1037 → 1174
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2285 → 2692
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:433 → 718
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3234 → 3561
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2782 → 3013
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3619 → 3702
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:459 → 490
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:790 → 842
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1395 → 1524
    UPA_2; UPA domain
    cl39094
    Location:590 → 814
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_036162849.1 → XP_036018742.1  ankyrin-2 isoform X44

    Conserved Domains (11) summary
    smart00218
    Location:954 → 1091
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2202 → 2609
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:8 → 316
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3151 → 3478
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2699 → 2930
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3536 → 3619
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:707 → 759
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1312 → 1441
    UPA_2; UPA domain
    pfam12796
    Location:381 → 472
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:456 → 731
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_036162846.1 → XP_036018739.1  ankyrin-2 isoform X41

    Conserved Domains (10) summary
    smart00218
    Location:965 → 1102
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2213 → 2620
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:383 → 668
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3162 → 3489
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2710 → 2941
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3547 → 3630
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1323 → 1452
    UPA_2; UPA domain
    cl39094
    Location:540 → 764
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_006500893.4 → XP_006500956.1  ankyrin-2 isoform X39

    Conserved Domains (10) summary
    smart00218
    Location:969 → 1106
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2217 → 2624
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:383 → 668
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3166 → 3493
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2714 → 2945
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3551 → 3634
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1327 → 1456
    UPA_2; UPA domain
    cl39094
    Location:540 → 764
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_036162835.1 → XP_036018728.1  ankyrin-2 isoform X26

    Conserved Domains (10) summary
    smart00218
    Location:987 → 1124
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2235 → 2642
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:383 → 668
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3184 → 3511
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2732 → 2963
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3569 → 3652
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1345 → 1474
    UPA_2; UPA domain
    cl39094
    Location:540 → 764
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_036162850.1 → XP_036018743.1  ankyrin-2 isoform X45

    Related
    ENSMUSP00000138620.4, ENSMUST00000182064.9
    Conserved Domains (10) summary
    smart00218
    Location:940 → 1077
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2188 → 2595
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:378 → 663
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3137 → 3464
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2685 → 2916
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3522 → 3605
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:404 → 435
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:735 → 787
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1298 → 1427
    UPA_2; UPA domain
    cl39094
    Location:535 → 759
    Ank_2; Ankyrin repeats (3 copies)

  11. XM_036162840.1 → XP_036018733.1  ankyrin-2 isoform X33

    Conserved Domains (10) summary
    smart00218
    Location:979 → 1116
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2227 → 2634
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:375 → 660
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3176 → 3503
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2724 → 2955
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3561 → 3644
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:401 → 432
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:732 → 784
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1337 → 1466
    UPA_2; UPA domain
    cl39094
    Location:532 → 756
    Ank_2; Ankyrin repeats (3 copies)

  12. XM_036162829.1 → XP_036018722.1  ankyrin-2 isoform X18

    Conserved Domains (10) summary
    smart00218
    Location:1012 → 1149
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2260 → 2667
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:408 → 693
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3209 → 3536
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2757 → 2988
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3594 → 3677
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:434 → 465
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:765 → 817
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1370 → 1499
    UPA_2; UPA domain
    cl39094
    Location:565 → 789
    Ank_2; Ankyrin repeats (3 copies)

  13. XM_036162836.1 → XP_036018729.1  ankyrin-2 isoform X27

    Conserved Domains (10) summary
    smart00218
    Location:987 → 1124
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2235 → 2642
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:392 → 668
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3184 → 3511
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2732 → 2963
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3569 → 3652
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:409 → 440
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1345 → 1474
    UPA_2; UPA domain
    cl39094
    Location:540 → 764
    Ank_2; Ankyrin repeats (3 copies)

  14. XM_036162837.1 → XP_036018730.1  ankyrin-2 isoform X29

    Conserved Domains (11) summary
    smart00218
    Location:987 → 1124
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2235 → 2642
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:39 → 349
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3184 → 3511
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2732 → 2963
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3569 → 3652
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:442 → 473
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1345 → 1474
    UPA_2; UPA domain
    pfam12796
    Location:414 → 505
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:489 → 764
    Ank_2; Ankyrin repeats (3 copies)

  15. XM_036162825.1 → XP_036018718.1  ankyrin-2 isoform X14

    Conserved Domains (10) summary
    smart00218
    Location:1020 → 1157
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2268 → 2675
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:416 → 701
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3217 → 3544
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2765 → 2996
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3602 → 3685
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:442 → 473
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:773 → 825
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1378 → 1507
    UPA_2; UPA domain
    cl39094
    Location:573 → 797
    Ank_2; Ankyrin repeats (3 copies)

  16. XM_036162843.1 → XP_036018736.1  ankyrin-2 isoform X36

    Conserved Domains (10) summary
    smart00218
    Location:974 → 1111
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2222 → 2629
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:370 → 655
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3171 → 3498
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2719 → 2950
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3556 → 3639
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:396 → 427
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:727 → 779
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1332 → 1461
    UPA_2; UPA domain
    cl39094
    Location:527 → 751
    Ank_2; Ankyrin repeats (3 copies)

  17. XM_036162839.1 → XP_036018732.1  ankyrin-2 isoform X32

    Conserved Domains (10) summary
    smart00218
    Location:982 → 1119
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2230 → 2637
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:378 → 663
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3179 → 3506
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2727 → 2958
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3564 → 3647
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:404 → 435
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:735 → 787
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1340 → 1469
    UPA_2; UPA domain
    cl39094
    Location:535 → 759
    Ank_2; Ankyrin repeats (3 copies)

  18. XM_036162852.1 → XP_036018745.1  ankyrin-2 isoform X47

    Conserved Domains (10) summary
    smart00218
    Location:873 → 1010
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2121 → 2528
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3070 → 3397
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2618 → 2849
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3455 → 3538
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1231 → 1360
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  19. XM_036162847.1 → XP_036018740.1  ankyrin-2 isoform X42

    Conserved Domains (10) summary
    smart00218
    Location:961 → 1098
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2209 → 2616
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:375 → 660
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3158 → 3485
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2706 → 2937
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3543 → 3626
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:401 → 432
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:732 → 784
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1319 → 1448
    UPA_2; UPA domain
    cl39094
    Location:532 → 756
    Ank_2; Ankyrin repeats (3 copies)

  20. XM_036162851.1 → XP_036018744.1  ankyrin-2 isoform X46

    Conserved Domains (11) summary
    smart00218
    Location:936 → 1073
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02876
    Location:260 → 600
    PHA02876; ankyrin repeat protein; Provisional
    PTZ00449
    Location:2184 → 2591
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:39 → 349
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3133 → 3460
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2681 → 2912
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3518 → 3601
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:640 → 671
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:707 → 759
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1294 → 1423
    UPA_2; UPA domain
    cl39094
    Location:507 → 731
    Ank_2; Ankyrin repeats (3 copies)

  21. XM_030252368.2 → XP_030108228.1  ankyrin-2 isoform X40

    Conserved Domains (11) summary
    smart00218
    Location:969 → 1106
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2217 → 2624
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:39 → 349
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3166 → 3493
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2714 → 2945
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3551 → 3634
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:442 → 473
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:414 → 505
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:740 → 792
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1327 → 1456
    UPA_2; UPA domain
    cl39094
    Location:489 → 764
    Ank_2; Ankyrin repeats (3 copies)

  22. XM_030252365.2 → XP_030108225.1  ankyrin-2 isoform X30

    Conserved Domains (10) summary
    smart00218
    Location:985 → 1122
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2233 → 2640
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:416 → 701
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3182 → 3509
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2730 → 2961
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3567 → 3650
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:442 → 473
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:773 → 825
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1343 → 1472
    UPA_2; UPA domain
    cl39094
    Location:573 → 797
    Ank_2; Ankyrin repeats (3 copies)

  23. XM_006500886.4 → XP_006500949.1  ankyrin-2 isoform X23

    Conserved Domains (10) summary
    smart00218
    Location:1002 → 1139
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2250 → 2657
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:416 → 701
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3199 → 3526
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2747 → 2978
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3584 → 3667
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:442 → 473
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:773 → 825
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1360 → 1489
    UPA_2; UPA domain
    cl39094
    Location:573 → 797
    Ank_2; Ankyrin repeats (3 copies)

  24. XM_036162831.1 → XP_036018724.1  ankyrin-2 isoform X20

    Conserved Domains (10) summary
    smart00218
    Location:1066 → 1203
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2314 → 2721
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:462 → 747
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3263 → 3590
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2811 → 3042
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3648 → 3731
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:488 → 519
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:819 → 871
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1424 → 1553
    UPA_2; UPA domain
    cl39094
    Location:619 → 843
    Ank_2; Ankyrin repeats (3 copies)

  25. XM_036162824.1 → XP_036018717.1  ankyrin-2 isoform X13

    Conserved Domains (10) summary
    smart00218
    Location:1054 → 1158
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2269 → 2676
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:462 → 747
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3218 → 3545
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2766 → 2997
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3603 → 3686
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:488 → 519
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:819 → 871
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1379 → 1508
    UPA_2; UPA domain
    cl39094
    Location:619 → 843
    Ank_2; Ankyrin repeats (3 copies)

  26. XM_036162827.1 → XP_036018720.1  ankyrin-2 isoform X16

    Conserved Domains (10) summary
    smart00218
    Location:1046 → 1150
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2261 → 2668
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:462 → 747
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3210 → 3537
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2758 → 2989
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3595 → 3678
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:488 → 519
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:819 → 871
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1371 → 1500
    UPA_2; UPA domain
    cl39094
    Location:619 → 843
    Ank_2; Ankyrin repeats (3 copies)

  27. XM_036162853.1 → XP_036018746.1  ankyrin-2 isoform X48

    Conserved Domains (7) summary
    smart00218
    Location:1066 → 1203
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:462 → 747
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1582 → 1665
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:488 → 519
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:819 → 871
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1424 → 1553
    UPA_2; UPA domain
    cl39094
    Location:619 → 843
    Ank_2; Ankyrin repeats (3 copies)

  28. XM_011239990.1 → XP_011238292.1  ankyrin-2 isoform X8

    Conserved Domains (10) summary
    smart00218
    Location:846 → 983
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2094 → 2501
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3043 → 3370
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2591 → 2822
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3428 → 3511
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1204 → 1333
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  29. XM_011239986.1 → XP_011238288.1  ankyrin-2 isoform X7

    Conserved Domains (10) summary
    smart00218
    Location:851 → 988
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2099 → 2506
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3048 → 3375
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2596 → 2827
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3433 → 3516
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1209 → 1338
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  30. XM_036162817.1 → XP_036018710.1  ankyrin-2 isoform X4

    Conserved Domains (10) summary
    smart00218
    Location:864 → 1001
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2112 → 2519
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3061 → 3388
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2609 → 2840
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3446 → 3529
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1222 → 1351
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  31. XM_036162818.1 → XP_036018711.1  ankyrin-2 isoform X5

    Conserved Domains (10) summary
    smart00218
    Location:861 → 998
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2109 → 2516
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3058 → 3385
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2606 → 2837
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3443 → 3526
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1219 → 1348
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  32. XM_036162814.1 → XP_036018707.1  ankyrin-2 isoform X1

    Conserved Domains (10) summary
    smart00218
    Location:869 → 1006
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2117 → 2524
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3066 → 3393
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2614 → 2845
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3451 → 3534
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1227 → 1356
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  33. XM_036162815.1 → XP_036018708.1  ankyrin-2 isoform X2

    Conserved Domains (10) summary
    smart00218
    Location:868 → 1005
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2116 → 2523
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3065 → 3392
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2613 → 2844
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3450 → 3533
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1226 → 1355
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  34. XM_036162819.1 → XP_036018712.1  ankyrin-2 isoform X6

    Conserved Domains (10) summary
    smart00218
    Location:853 → 990
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2101 → 2508
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3050 → 3377
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2598 → 2829
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3435 → 3518
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1211 → 1340
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  35. XM_036162816.1 → XP_036018709.1  ankyrin-2 isoform X3

    Conserved Domains (10) summary
    smart00218
    Location:865 → 1002
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2113 → 2520
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3062 → 3389
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2610 → 2841
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3447 → 3530
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1223 → 1352
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  36. XM_036162821.1 → XP_036018714.1  ankyrin-2 isoform X10

    Conserved Domains (10) summary
    smart00218
    Location:873 → 977
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2088 → 2495
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:269 → 554
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3037 → 3364
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2585 → 2816
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3422 → 3505
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:295 → 326
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:626 → 678
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1198 → 1327
    UPA_2; UPA domain
    cl39094
    Location:426 → 650
    Ank_2; Ankyrin repeats (3 copies)

  37. XM_036162845.1 → XP_036018738.1  ankyrin-2 isoform X38

    Conserved Domains (11) summary
    smart00218
    Location:967 → 1104
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2215 → 2622
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:27 → 329
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3164 → 3491
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2712 → 2943
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3549 → 3632
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:422 → 453
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:720 → 772
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1325 → 1454
    UPA_2; UPA domain
    pfam12796
    Location:394 → 485
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:469 → 744
    Ank_2; Ankyrin repeats (3 copies)

  38. XM_036162833.1 → XP_036018726.1  ankyrin-2 isoform X22

    Conserved Domains (10) summary
    smart00218
    Location:1000 → 1137
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2248 → 2655
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:396 → 681
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3197 → 3524
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2745 → 2976
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3582 → 3665
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:422 → 453
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:753 → 805
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1358 → 1487
    UPA_2; UPA domain
    cl39094
    Location:553 → 777
    Ank_2; Ankyrin repeats (3 copies)

  39. XM_036162841.1 → XP_036018734.1  ankyrin-2 isoform X34

    UniProtKB/TrEMBL
    S4R2F3
    Conserved Domains (10) summary
    smart00218
    Location:975 → 1112
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2223 → 2630
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:380 → 656
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3172 → 3499
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2720 → 2951
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3557 → 3640
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:397 → 428
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:728 → 780
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1333 → 1462
    UPA_2; UPA domain
    cl39094
    Location:528 → 752
    Ank_2; Ankyrin repeats (3 copies)

  40. XM_036162848.1 → XP_036018741.1  ankyrin-2 isoform X43

    UniProtKB/TrEMBL
    S4R2F3
    Conserved Domains (11) summary
    smart00218
    Location:957 → 1094
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2205 → 2612
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:27 → 337
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3154 → 3481
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2702 → 2933
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3539 → 3622
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:728 → 780
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1315 → 1444
    UPA_2; UPA domain
    pfam12796
    Location:402 → 493
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:477 → 752
    Ank_2; Ankyrin repeats (3 copies)

  41. XM_036162842.1 → XP_036018735.1  ankyrin-2 isoform X35

    UniProtKB/TrEMBL
    S4R2F3
    Conserved Domains (11) summary
    smart00218
    Location:975 → 1112
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2223 → 2630
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:27 → 337
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3172 → 3499
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2720 → 2951
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3557 → 3640
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:728 → 780
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1333 → 1462
    UPA_2; UPA domain
    pfam12796
    Location:402 → 493
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:477 → 752
    Ank_2; Ankyrin repeats (3 copies)

  42. XM_036162830.1 → XP_036018723.1  ankyrin-2 isoform X19

    UniProtKB/TrEMBL
    S4R2F3
    Conserved Domains (10) summary
    smart00218
    Location:1008 → 1145
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2256 → 2663
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:404 → 689
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3205 → 3532
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2753 → 2984
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3590 → 3673
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:761 → 813
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1366 → 1495
    UPA_2; UPA domain
    cl39094
    Location:561 → 785
    Ank_2; Ankyrin repeats (3 copies)

  43. XM_036162838.1 → XP_036018731.1  ankyrin-2 isoform X31

    Conserved Domains (10) summary
    smart00218
    Location:982 → 1119
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2230 → 2637
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:396 → 681
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3179 → 3506
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2727 → 2958
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3564 → 3647
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:422 → 453
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:753 → 805
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1340 → 1469
    UPA_2; UPA domain
    cl39094
    Location:553 → 777
    Ank_2; Ankyrin repeats (3 copies)

  44. XM_017319427.2 → XP_017174916.1  ankyrin-2 isoform X24

    Conserved Domains (10) summary
    smart00218
    Location:997 → 1134
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2245 → 2652
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:411 → 696
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3194 → 3521
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2742 → 2973
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3579 → 3662
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:437 → 468
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:768 → 820
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1355 → 1484
    UPA_2; UPA domain
    cl39094
    Location:568 → 792
    Ank_2; Ankyrin repeats (3 copies)

  45. XM_036162823.1 → XP_036018716.1  ankyrin-2 isoform X12

    Conserved Domains (10) summary
    smart00218
    Location:1023 → 1160
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2271 → 2678
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:419 → 704
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3220 → 3547
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2768 → 2999
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3605 → 3688
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:445 → 476
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:776 → 828
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1381 → 1510
    UPA_2; UPA domain
    cl39094
    Location:576 → 800
    Ank_2; Ankyrin repeats (3 copies)

  46. XM_036162826.1 → XP_036018719.1  ankyrin-2 isoform X15

    Conserved Domains (10) summary
    smart00218
    Location:1015 → 1152
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2263 → 2670
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:411 → 696
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3212 → 3539
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2760 → 2991
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3597 → 3680
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:437 → 468
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:768 → 820
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1373 → 1502
    UPA_2; UPA domain
    cl39094
    Location:568 → 792
    Ank_2; Ankyrin repeats (3 copies)

  47. XM_036162855.1 → XP_036018748.1  ankyrin-2 isoform X50

    Conserved Domains (10) summary
    smart00218
    Location:1005 → 1142
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2253 → 2660
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:413 → 698
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3202 → 3529
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2750 → 2981
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3587 → 3670
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:770 → 822
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1363 → 1492
    UPA_2; UPA domain
    cl39094
    Location:570 → 794
    Ank_2; Ankyrin repeats (3 copies)

  48. XM_036162854.1 → XP_036018747.1  ankyrin-2 isoform X49

    Conserved Domains (10) summary
    smart00218
    Location:1013 → 1150
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2261 → 2668
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:421 → 706
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3210 → 3537
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2758 → 2989
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3595 → 3678
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:447 → 478
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:778 → 830
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1371 → 1500
    UPA_2; UPA domain
    cl39094
    Location:578 → 802
    Ank_2; Ankyrin repeats (3 copies)

  49. XM_036162822.1 → XP_036018715.1  ankyrin-2 isoform X11

    Conserved Domains (10) summary
    smart00218
    Location:1025 → 1162
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2273 → 2680
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:421 → 706
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3222 → 3549
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2770 → 3001
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3607 → 3690
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:447 → 478
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:778 → 830
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1383 → 1512
    UPA_2; UPA domain
    cl39094
    Location:578 → 802
    Ank_2; Ankyrin repeats (3 copies)

  50. XM_036162828.1 → XP_036018721.1  ankyrin-2 isoform X17

    Conserved Domains (10) summary
    smart00218
    Location:1013 → 1150
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2261 → 2668
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:421 → 706
    PHA03095; ankyrin-like protein; Provisional
    PHA03307
    Location:3210 → 3537
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5665
    Location:2758 → 2989
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    cd08804
    Location:3595 → 3678
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:447 → 478
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:778 → 830
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1371 → 1500
    UPA_2; UPA domain
    cl39094
    Location:578 → 802
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C8R3.2 GenPept UniProtKB/Swiss-Prot:Q8C8R3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous