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Gm12258 predicted gene 12258 [ Mus musculus (house mouse) ]

Gene ID: 108167848, updated on 30-Apr-2024

Summary

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Official Symbol
Gm12258provided by MGI
Official Full Name
predicted gene 12258provided by MGI
Primary source
MGI:MGI:3651534
See related
Ensembl:ENSMUSG00000072915 AllianceGenome:MGI:3651534
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 9.3), CNS E14 (RPKM 9.0) and 23 other tissues See more
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Genomic context

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Location:
11 B1.3; 11 36.33 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58737971..58752783)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58847162..58861957)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AF member 1 Neighboring gene STARR-positive B cell enhancer ABC_E588 Neighboring gene olfactory receptor family 9 subfamily E member 1 Neighboring gene RIKEN cDNA 2810021J22 gene Neighboring gene STARR-positive B cell enhancer ABC_E9824 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697199-58697308 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697335-58697545 Neighboring gene zinc finger protein 39 Neighboring gene STARR-positive B cell enhancer ABC_E2990 Neighboring gene predicted gene 12257

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC108167848
Names
part of a novel protein
zinc finger protein 717-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001372581.1 → NP_001359510.1  uncharacterized protein LOC108167848 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL662903, CN460644
    Consensus CDS
    CCDS88162.1
    UniProtKB/TrEMBL
    Q5NC63
    Related
    ENSMUSP00000117644.3, ENSMUST00000139337.3
    Conserved Domains (5) summary
    smart00349
    Location:8 → 67
    KRAB; krueppel associated box
    COG5048
    Location:412 → 608
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:488 → 508
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:249 → 269
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:598 → 620
    zf-C2H2; Zinc finger, C2H2 type

  2. NM_001372582.1 → NP_001359511.1  uncharacterized protein LOC108167848 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL662903
    Conserved Domains (5) summary
    COG5048
    Location:376 → 572
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:452 → 472
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:213 → 233
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:562 → 584
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 31
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    58737971..58752783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156222.1 → XP_036012115.1  uncharacterized protein LOC108167848 isoform X1

    Conserved Domains (5) summary
    COG5048
    Location:376 → 572
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:452 → 472
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:213 → 233
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:562 → 584
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 31
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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