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LOC108167305 Clec2l Hedgehog-responsive enhancer [ Mus musculus (house mouse) ]

Gene ID: 108167305, updated on 8-Feb-2024

Summary

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Gene symbol
LOC108167305
Gene description
Clec2l Hedgehog-responsive enhancer
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366685
Summary
This genomic region is in an intron of the Clec2l (C-type lectin domain family 2, member L) gene, which is located approximately 33 kb from the 3' end of the Hipk2 (homeodomain interacting protein kinase 2) gene. This region was predicted to be a Hedgehog (Hh)-responsive enhancer based on the presence of GLI family zinc finger binding motifs, and it was validated as a functional Hh enhancer in reporter gene assays. [provided by RefSeq, Jun 2016]
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Genomic context

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Location:
6 B1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (38640936..38642118)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (38664001..38665183)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2782 Neighboring gene kinesin family member 11 pseudogene Neighboring gene LUC7-like 2 (S. cerevisiae) Neighboring gene killer cell lectin-like receptor subfamily G, member 2 Neighboring gene C-type lectin domain family 2, member L Neighboring gene homeodomain interacting protein kinase 2 Neighboring gene STARR-positive B cell enhancer mm9_chr6:38676623-38676923 Neighboring gene STARR-positive B cell enhancer mm9_chr6:38677325-38677625 Neighboring gene predicted gene, 53285 Neighboring gene RIKEN cDNA 4930502C15 gene Neighboring gene Hipk2R16 erythroid cis-regulatory module

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Computational prediction and experimental validation of novel Hedgehog-responsive enhancers linked to genes of the Hedgehog pathway. Gurdziel K, et al. BMC Dev Biol, 2016 Feb 24. PMID 26912062, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • C-type lectin domain family 2, member L Hh-responsive enhancer
  • Hipk2 Hedgehog-responsive enhancer
  • regulatory region 366685

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050894.1 

    Range
    101..1283
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    38640936..38642118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version