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Ugt3a1 UDP glycosyltransferases 3 family, polypeptide A1 [ Mus musculus (house mouse) ]

Gene ID: 105887, updated on 5-Mar-2024

Summary

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Official Symbol
Ugt3a1provided by MGI
Official Full Name
UDP glycosyltransferases 3 family, polypeptide A1provided by MGI
Primary source
MGI:MGI:2146055
See related
Ensembl:ENSMUSG00000072664 AllianceGenome:MGI:2146055
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables UDP-glycosyltransferase activity. Predicted to act upstream of or within cellular response to genistein. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in trigeminal ganglion. Orthologous to several human genes including UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 77.1) and liver adult (RPKM 30.5) See more
Orthologs
human all
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Genomic context

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Location:
15; 15 A1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (9279908..9315124)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (9279822..9315038)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3131 Neighboring gene S-phase kinase-associated protein 2 Neighboring gene LMBR1 domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_37931 Neighboring gene STARR-seq mESC enhancer starr_37932 Neighboring gene UDP glycosyltransferases 3 family pseudogene Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene UDP glycosyltransferases 3 family, polypeptide A2 Neighboring gene STARR-seq mESC enhancer starr_37936

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes. Meech R, et al. J Biol Chem, 2012 Jul 13. PMID 22621930, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-glycosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables glucuronosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to genistein ISO
Inferred from Sequence Orthology
more info
 PubMed 
Component Evidence Code Pubs
part_of UDP-N-acetylglucosamine transferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of UDP-N-acetylglucosamine transferase complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-glucuronosyltransferase 3A1
Names
UDP glucuronosyltransferase 3 family, polypeptide A1
UDPGT 3A1
NP_997099.2
XP_006520074.1
XP_006520075.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207216.2 → NP_997099.2  UDP-glucuronosyltransferase 3A1 precursor

    See identical proteins and their annotated locations for NP_997099.2

    Status: VALIDATED

    Source sequence(s)
    AC132893, AI746748, AK143745, BY006031
    Consensus CDS
    CCDS27374.1
    UniProtKB/Swiss-Prot
    Q3UP75, Q8R0Y5
    Related
    ENSMUSP00000022861.9, ENSMUST00000022861.9
    Conserved Domains (2) summary
    PHA03392
    Location:235 → 488
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:24 → 488
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    9279908..9315124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520012.4 → XP_006520075.1  UDP-glucuronosyltransferase 3A1 isoform X2

    Conserved Domains (1) summary
    pfam00201
    Location:24 → 281
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  2. XM_006520011.3 → XP_006520074.1  UDP-glucuronosyltransferase 3A1 isoform X1

    Conserved Domains (1) summary
    pfam00201
    Location:1 → 359
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UP75.1 GenPept UniProtKB/Swiss-Prot:Q3UP75

Gene LinkOut

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