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CELP carboxyl ester lipase pseudogene [ Homo sapiens (human) ]

Gene ID: 1057, updated on 10-Oct-2023

Summary

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Official Symbol
CELPprovided by HGNC
Official Full Name
carboxyl ester lipase pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:1849
See related
Ensembl:ENSG00000170827 AllianceGenome:HGNC:1849
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CELL; cell1; cell2; cell3
Expression
Restricted expression toward pancreas (RPKM 10770.7) See more
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Genomic context

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See CELP in Genome Data Viewer
Location:
9q34.13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (133082539..133087091)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (145276137..145301213)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (135957926..135962478)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene general transcription factor IIIC subunit 5 Neighboring gene uncharacterized LOC124902325 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:135935579-135936330 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:135936331-135937083 Neighboring gene carboxyl ester lipase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135965875-135966376 Neighboring gene small nucleolar RNA U13 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:135976589-135977788 Neighboring gene ral guanine nucleotide dissociation stimulator Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29228 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:135995531-135996227 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20442 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20444 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20445 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr9:136002206-136003405 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136008097-136008641 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29229 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29230 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29231 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29233 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136019197-136019756 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20446 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20447 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136024237-136024884

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. No Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations. Zou WB, et al. Gastroenterology, 2016 Jun. PMID 26946345, Free PMC Article
  2. Processed pseudogenes: characteristics and evolution. Vanin EF. Annu Rev Genet, 1985. PMID 3909943
  3. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Fjeld K, et al. Nat Genet, 2015 May. PMID 25774637, Free PMC Article
  4. The human carboxyl ester lipase-like (CELL) gene is ubiquitously expressed and contains a hypervariable region. Nilsson J, et al. Genomics, 1993 Aug. PMID 7691717
  5. Genomic organization, sequence analysis, and chromosomal localization of the human carboxyl ester lipase (CEL) gene and a CEL-like (CELL) gene. Lidberg U, et al. Genomics, 1992 Jul. PMID 1639390

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • carboxyl ester lipase-like (bile salt-stimulated lipase-like)

Clone Names

  • FLJ25862

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_001275.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL162417, AW582943, L14813
    Related
    ENST00000421286.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    133082539..133087091
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    145276137..145301213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001808.1: Suppressed sequence

    Description
    NM_001808.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version

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