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E330034G19Rik RIKEN cDNA E330034G19 gene [ Mus musculus (house mouse) ]

Gene ID: 105418, updated on 8-Feb-2024

Summary

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Official Symbol
E330034G19Rikprovided by MGI
Official Full Name
RIKEN cDNA E330034G19 geneprovided by MGI
Primary source
MGI:MGI:2145557
See related
Ensembl:ENSMUSG00000121465 AllianceGenome:MGI:2145557
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zpac
Summary
Acts upstream of or within positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Is expressed in oocyte and ovary. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 1.8) and ovary adult (RPKM 0.8) See more
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Genomic context

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Location:
14 A3; 14 14.33 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (24343282..24360028)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (24293214..24309960)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 5 Neighboring gene predicted gene, 52143 Neighboring gene STARR-seq mESC enhancer starr_36186 Neighboring gene VISTA enhancer mm1485 Neighboring gene STARR-seq mESC enhancer starr_36187 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide A pseudogene Neighboring gene STARR-seq mESC enhancer starr_36189 Neighboring gene STARR-seq mESC enhancer starr_36191 Neighboring gene cysteine rich protein 2 pseudogene Neighboring gene predicted gene, 41108

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. ZPAC is required for normal spermatogenesis in mice. Zuo EW, et al. Mol Reprod Dev, 2015 Oct. PMID 26153379
  2. Possible role of ZPAC, zygote-specific proteasome assembly chaperone, during spermatogenesis in the mouse. Shimizu N, et al. J Reprod Dev, 2014. PMID 24583807, Free PMC Article
  3. Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition. Shin SW, et al. Biol Open, 2013 Feb 15. PMID 23429752, Free PMC Article
  4. Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor. Joshi S, et al. BMC Dev Biol, 2007 Jun 13. PMID 17567914, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Protein E330034G19Rik
Names
zygote-specific proteasome assembly chaperone

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033214.2 → NP_001028386.1  Protein E330034G19Rik isoform 1

    See identical proteins and their annotated locations for NP_001028386.1

    Status: VALIDATED

    Source sequence(s)
    AK136036
    Consensus CDS
    CCDS49418.1
    UniProtKB/TrEMBL
    E9PWE7, Q3UWX6, Q8C2V6
    Related
    ENSMUST00000239244.2
    Conserved Domains (2) summary
    cd16269
    Location:289 → 300
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:250 → 313
    GBP_C; Guanylate-binding protein, C-terminal domain

  2. NM_001346536.1 → NP_001333465.1  Protein E330034G19Rik isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC161374, BG067232, CA555840
    Consensus CDS
    CCDS88596.1
    UniProtKB/TrEMBL
    Q8C2V6
    Related
    ENSMUST00000162224.8

  3. NM_001379547.1 → NP_001366476.1  Protein E330034G19Rik isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC161374
    UniProtKB/TrEMBL
    Q8C2V6
    Conserved Domains (1) summary
    TIGR02168
    Location:15 → 278
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    24343282..24360028
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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