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FLNB-AS1 FLNB antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 105377105, updated on 10-Oct-2023

Summary

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Official Symbol
FLNB-AS1provided by HGNC
Official Full Name
FLNB antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:40239
See related
Ensembl:ENSG00000244161 AllianceGenome:HGNC:40239
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in prostate (RPKM 4.2), colon (RPKM 4.0) and 25 other tissues See more
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Genomic context

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See FLNB-AS1 in Genome Data Viewer
Location:
3p14.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (58162547..58170635, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (58203004..58211092, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (58148274..58156362, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57944346-57944927 Neighboring gene peptidylprolyl isomerase A pseudogene 16 Neighboring gene uncharacterized LOC105377104 Neighboring gene PPIAP16-FLNB intergenic CAGE-defined mid-level expression enhancer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57946764-57947718 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57947719-57948671 Neighboring gene Sharpr-MPRA regulatory region 380 Neighboring gene uncharacterized LOC124909385 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57958837-57959340 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57959341-57959842 Neighboring gene PPIAP16-FLNB intergenic CAGE-defined low expression enhancer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57983544-57984119 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:57999317-57999817 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:57999844-58000357 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58000358-58000870 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58000871-58001384 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58005500-58006482 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58006483-58007463 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58007464-58008445 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:58020595-58021094 Neighboring gene filamin B Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:58023882-58024382 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58025201-58025780 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58027143-58027657 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58028173-58028686 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:58034417-58035616 Neighboring gene Sharpr-MPRA regulatory region 2534 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58040937-58041474 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58051153-58052030 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19999 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14485 Neighboring gene Sharpr-MPRA regulatory region 3708 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:58147281-58148480 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:58149790-58150603 Neighboring gene Sharpr-MPRA regulatory region 1271 Neighboring gene uncharacterized LOC124909485 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20000 Neighboring gene uncharacterized LOC124909386

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. Choudhury NR, et al. BMC Biol, 2017 Nov 8. PMID 29117863, Free PMC Article
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Other Names

  • FLNB antisense RNA 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_135534.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BC041347, DB066566
    Related
    ENST00000488720.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    58162547..58170635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    58203004..58211092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases