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Mir133a-1hg Mir133a-1, Mir1b and Mir1a-2 host gene [ Mus musculus (house mouse) ]

Gene ID: 105246366, updated on 25-Apr-2024

Summary

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Official Symbol
Mir133a-1hgprovided by MGI
Official Full Name
Mir133a-1, Mir1b and Mir1a-2 host geneprovided by MGI
Primary source
MGI:MGI:5433911
See related
AllianceGenome:MGI:5433911
Gene type
ncRNA
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm21747
Summary
Involved in negative regulation of gene expression. Acts upstream of or within locomotory behavior and mitochondrion organization. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
18 A1; 18
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (10781723..10791734, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (10778306..10791393, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930563E18 gene Neighboring gene MIB E3 ubiquitin protein ligase 1 Neighboring gene predicted gene, 25116 Neighboring gene microRNA 133a-1 Neighboring gene microRNA 1a-2 Neighboring gene microRNA 1b Neighboring gene STARR-seq mESC enhancer starr_43802 Neighboring gene STARR-seq mESC enhancer starr_43806 Neighboring gene apurinic/apyrimidinic endonuclease 1 pseudogene Neighboring gene predicted gene, 35814 Neighboring gene PHD finger protein 14 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. Klockner I, et al. Nat Commun, 2022 Jun 8. PMID 35676269, Free PMC Article
  2. Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. Valussi M, et al. Sci Adv, 2021 Oct 15. PMID 34644107, Free PMC Article
  3. Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster. Wüst S, et al. Cell Metab, 2018 May 1. PMID 29606596
  4. miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart development. Wystub K, et al. PLoS Genet, 2013. PMID 24068960, Free PMC Article
  5. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of gene expression IDA
Inferred from Direct Assay
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    10781723..10791734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_877177.4 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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