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Fam110c family with sequence similarity 110, member C [ Mus musculus (house mouse) ]

Gene ID: 104943, updated on 5-Mar-2024

Summary

Official Symbol
Fam110cprovided by MGI
Official Full Name
family with sequence similarity 110, member Cprovided by MGI
Primary source
MGI:MGI:1918813
See related
Ensembl:ENSMUSG00000036136 AllianceGenome:MGI:1918813
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9030611O19Rik
Summary
Predicted to enable alpha-tubulin binding activity. Predicted to be involved in positive regulation of cell migration; positive regulation of protein kinase B signaling; and regulation of cell projection assembly. Predicted to be located in cytoplasm; microtubule; and nucleus. Predicted to be active in cell cortex. Is expressed in adrenal gland and pancreas epithelium. Orthologous to human FAM110C (family with sequence similarity 110 member C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 8.1), bladder adult (RPKM 7.7) and 14 other tissues See more
Orthologs
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Genomic context

See Fam110c in Genome Data Viewer
Location:
12 A2; 12 13.06 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (31123967..31129939)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (31073968..31079940)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_31847 Neighboring gene predicted gene, 25408 Neighboring gene predicted gene, 32443 Neighboring gene predicted gene, 40361 Neighboring gene SCAN domain containing 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables alpha-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables alpha-tubulin binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027828.2NP_082104.2  protein FAM110C

    See identical proteins and their annotated locations for NP_082104.2

    Status: PROVISIONAL

    Source sequence(s)
    BC019466
    Consensus CDS
    CCDS25860.1
    UniProtKB/Swiss-Prot
    Q8VE94, Q9D322
    Related
    ENSMUSP00000041563.9, ENSMUST00000041133.10
    Conserved Domains (1) summary
    pfam14160
    Location:304409
    FAM110_C; Centrosome-associated C terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    31123967..31129939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)