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Mycbpap MYCBP associated protein [ Mus musculus (house mouse) ]

Gene ID: 104601, updated on 3-Apr-2024

Summary

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Official Symbol
Mycbpapprovided by MGI
Official Full Name
MYCBP associated proteinprovided by MGI
Primary source
MGI:MGI:2388726
See related
Ensembl:ENSMUSG00000039110 AllianceGenome:MGI:2388726
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AMAM-1; AMAP-1; 4932408B01Rik
Summary
Predicted to act upstream of or within cell differentiation and spermatogenesis. Predicted to be located in cytoplasm. Is expressed in 4th ventricle lateral recess; choroid plexus; lateral ventricle choroid plexus; and pancreas epithelium. Orthologous to human MYCBPAP (MYCBP associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 46.8) and lung adult (RPKM 2.1) See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 58.9 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94392173..94423219, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94501347..94532386, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3 Neighboring gene predicted gene, 51873 Neighboring gene predicted gene, 35650 Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. Yukitake H, et al. Biochim Biophys Acta, 2002 Aug 19. PMID 12151104
  2. The sperm-associated antigen 6 interactome and its role in spermatogenesis. Liu Y, et al. Reproduction, 2019 Aug. PMID 31146259, Free PMC Article
  3. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. differential gene expression of AMAP-1 during the course of spermatogenesis (AMAP-1)
    Title: AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MYCBP-associated protein
Names
AMY-1-binding protein 1
AMY1-associating protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001415760.1 → NP_001402689.1  MYCBP-associated protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645809
    UniProtKB/TrEMBL
    A0A668KL73
    Related
    ENSMUSP00000159222.2, ENSMUST00000239238.2

  2. NM_170671.3 → NP_733771.3  MYCBP-associated protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645809
    Consensus CDS
    CCDS48887.1
    Related
    ENSMUSP00000091477.4, ENSMUST00000093945.10

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    94392173..94423219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531938.5 → XP_006532001.1  MYCBP-associated protein isoform X1

    UniProtKB/Swiss-Prot
    Q5SUV2, Q80YS8, Q8R2Q9
    Conserved Domains (1) summary
    pfam14646
    Location:241 → 658
    MYCBPAP; MYCBP-associated protein family

  2. XM_006531939.4 → XP_006532002.1  MYCBP-associated protein isoform X2

    UniProtKB/Swiss-Prot
    Q5SUV2, Q80YS8, Q8R2Q9
    Conserved Domains (1) summary
    pfam14646
    Location:241 → 658
    MYCBPAP; MYCBP-associated protein family

RNA

  1. XR_388315.4 RNA Sequence

  2. XR_003949210.2 RNA Sequence

    Related
    ENSMUST00000123496.8
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SUV2.1 GenPept UniProtKB/Swiss-Prot:Q5SUV2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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