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Pcnx3 pecanex homolog 3 [ Mus musculus (house mouse) ]

Gene ID: 104401, updated on 5-Mar-2024

Summary

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Official Symbol
Pcnx3provided by MGI
Official Full Name
pecanex homolog 3provided by MGI
Primary source
MGI:MGI:1861733
See related
Ensembl:ENSMUSG00000054874 AllianceGenome:MGI:1861733
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pcnxl3; mKIAA4073
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human PCNX3 (pecanex 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 60.8), adrenal adult (RPKM 58.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Pcnx3 in Genome Data Viewer
Location:
19 A; 19 4.34 cM
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5714663..5739036, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5664635..5689003, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene v-rel reticuloendotheliosis viral oncogene homolog A (avian) Neighboring gene signal-induced proliferation associated gene 1 Neighboring gene microRNA 6987 Neighboring gene STARR-positive B cell enhancer ABC_E4259 Neighboring gene STARR-positive B cell enhancer ABC_E11012 Neighboring gene mitogen-activated protein kinase kinase kinase 11 Neighboring gene potassium channel, subfamily K, member 7 Neighboring gene EH domain binding protein 1-like 1 Neighboring gene family with sequence similarity 89, member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genomic sequencing reveals the structure of the Kcnk6 and map3k11 genes and their close vicinity to the sipa1 gene on mouse chromosome 19. Saridaki A, et al. Cytogenet Cell Genet, 2000. PMID 10894943
  2. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Park YG, et al. Nat Genet, 2005 Oct. PMID 16142231, Free PMC Article
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA4073

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
pecanex-like protein 3
Names
pecanex homolog protein 3
pecanex-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144868.3 → NP_659117.2  pecanex-like protein 3

    See identical proteins and their annotated locations for NP_659117.2

    Status: VALIDATED

    Source sequence(s)
    BC096538, BE956025
    Consensus CDS
    CCDS29475.2
    UniProtKB/Swiss-Prot
    Q8VI59
    Related
    ENSMUSP00000109245.3, ENSMUST00000113615.9
    Conserved Domains (2) summary
    pfam05041
    Location:1570 → 1795
    Pecanex_C; Pecanex protein (C-terminus)
    cl21589
    Location:419 → 622
    Relaxase; Relaxase/Mobilization nuclease domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5714663..5739036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531613.5 → XP_006531676.1  pecanex-like protein 3 isoform X2

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 654
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1865 → 2034
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1582 → 1808
    Pecanex_C; Pecanex protein (C-terminus)

  2. XM_030250681.1 → XP_030106541.1  pecanex-like protein 3 isoform X7

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 654
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1852 → 2021
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1569 → 1795
    Pecanex_C; Pecanex protein (C-terminus)

  3. XM_006531612.4 → XP_006531675.1  pecanex-like protein 3 isoform X1

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 655
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1866 → 2035
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1583 → 1809
    Pecanex_C; Pecanex protein (C-terminus)

  4. XM_030250679.1 → XP_030106539.1  pecanex-like protein 3 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 654
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1859 → 2028
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1576 → 1802
    Pecanex_C; Pecanex protein (C-terminus)

  5. XM_011248596.4 → XP_011246898.1  pecanex-like protein 3 isoform X9

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 655
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1843 → 2012
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1560 → 1786
    Pecanex_C; Pecanex protein (C-terminus)

  6. XM_006531615.5 → XP_006531678.1  pecanex-like protein 3 isoform X8

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 655
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1850 → 2019
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1567 → 1793
    Pecanex_C; Pecanex protein (C-terminus)

  7. XM_011248595.4 → XP_011246897.1  pecanex-like protein 3 isoform X5

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 655
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1856 → 2025
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1573 → 1799
    Pecanex_C; Pecanex protein (C-terminus)

  8. XM_006531614.5 → XP_006531677.1  pecanex-like protein 3 isoform X3

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 655
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1860 → 2029
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1577 → 1803
    Pecanex_C; Pecanex protein (C-terminus)

  9. XM_030250682.2 → XP_030106542.1  pecanex-like protein 3 isoform X10

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 654
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1842 → 2011
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1559 → 1785
    Pecanex_C; Pecanex protein (C-terminus)

  10. XM_030250680.2 → XP_030106540.1  pecanex-like protein 3 isoform X6

    Conserved Domains (3) summary
    PHA03247
    Location:194 → 654
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1855 → 2024
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1572 → 1798
    Pecanex_C; Pecanex protein (C-terminus)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VI59.2 GenPept UniProtKB/Swiss-Prot:Q8VI59

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