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Rpn1 ribophorin I [ Mus musculus (house mouse) ]

Gene ID: 103963, updated on 9-Dec-2024

Summary

Official Symbol
Rpn1provided by MGI
Official Full Name
ribophorin Iprovided by MGI
Primary source
MGI:MGI:98084
See related
Ensembl:ENSMUSG00000030062 AllianceGenome:MGI:98084
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpn-1; D6Wsu137e
Summary
Predicted to be involved in protein N-linked glycosylation via asparagine. Located in endoplasmic reticulum membrane and rough endoplasmic reticulum. Part of oligosaccharyltransferase complex. Is expressed in several structures, including alimentary system; brain; cranium; genitourinary system; and sensory organ. Orthologous to human RPN1 (ribophorin I). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 91.8), ovary adult (RPKM 79.9) and 28 other tissues See more
Orthologs
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Genomic context

See Rpn1 in Genome Data Viewer
Location:
6 D1; 6 39.13 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (88061455..88082286)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (88084473..88105304)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34872 Neighboring gene RAB7, member RAS oncogene family Neighboring gene predicted gene, 38855 Neighboring gene STARR-seq mESC enhancer starr_16574 Neighboring gene STARR-positive B cell enhancer ABC_E2195 Neighboring gene microRNA 6376 Neighboring gene predicted gene, 53293 Neighboring gene Gata2R1 erythroid cis-regulatory module Neighboring gene stem and progenitor enriched required for hematopoietic differentiation Neighboring gene predicted gene, 38856

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol  
located_in cytosol  
located_in endoplasmic reticulum  
located_in endoplasmic reticulum membrane PubMed 
located_in endoplasmic reticulum membrane PubMed 
part_of oligosaccharyltransferase complex  
part_of oligosaccharyltransferase complex PubMed 
part_of oligosaccharyltransferase complex  
part_of oligosaccharyltransferase complex PubMed 
located_in rough endoplasmic reticulum PubMed 

General protein information

Preferred Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Names
RPN-I
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit
ribophorin-1
NP_598694.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133933.4NP_598694.3  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor

    See identical proteins and their annotated locations for NP_598694.3

    Status: VALIDATED

    Source sequence(s)
    AK029923, BC085483, BY308146
    Consensus CDS
    CCDS20332.1
    UniProtKB/Swiss-Prot
    Q3U985, Q91YQ5
    UniProtKB/TrEMBL
    Q3U900, Q5RKP4, Q8BMR3
    Related
    ENSMUSP00000032143.7, ENSMUST00000032143.8
    Conserved Domains (2) summary
    pfam04597
    Location:34458
    Ribophorin_I; Ribophorin I
    pfam10482
    Location:520590
    CtIP_N; Tumour-suppressor protein CtIP N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    88061455..88082286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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