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CDR1 cerebellar degeneration related 1 [ Homo sapiens (human) ]

Gene ID: 1038, updated on 5-Mar-2024

Summary

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Official Symbol
CDR1provided by HGNC
Official Full Name
cerebellar degeneration related 1provided by HGNC
Primary source
HGNC:HGNC:1798
See related
MIM:302650; AllianceGenome:HGNC:1798
Gene type
unknown
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CDR; CDR34; CDR62A
Orthologs
all

Genomic context

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Location:
Xq27.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (140772083..140793212, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (139089454..139110579, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373344 Neighboring gene NANOG hESC enhancer GRCh37_chrX:139608152-139608653 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:139655621-139655814 Neighboring gene uncharacterized LOC101928833 Neighboring gene NANOG hESC enhancer GRCh37_chrX:139805503-139806004 Neighboring gene long intergenic non-protein coding RNA 632 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:139865334-139866831 Neighboring gene microRNA 320d-2 Neighboring gene SPANX family member B1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
    Title: Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
  2. Our study confirmed that the circ_0001946/miR-671-5p/ CDR1 pathway modulates the development of glioblastoma
    Title: Circular RNA circ_0001946 acts as a competing endogenous RNA to inhibit glioblastoma progression by modulating miR-671-5p and CDR1.
  3. Underexpression of CDR1 is associated with glioblastoma multiforme.
    Title: Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.
  4. The results of this case-control study showed that the CDR1 gene was over-expressed in five out of seven subjects with AD compared to seven age- and sex-matched normal controls. Data suggest that CDR1 gene may play a role, in Alzheimer's disease process.
    Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease.
  5. The CDR1 gene was overexpressed in the LNCaP and PC-3 PCa cell lines as compared with the PNT1A normal prostate cell line.
    Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in prostate cancer cell lines.
  6. Treatment of systemic lupus erythematosus afflicted (NZBxNZW)F1 mice with human CDR1 down regulated gene expression of IFN-alpha.
    Title: The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus.
  7. miR-671 directs cleavage of a circular antisense transcript of the Cerebellar Degeneration-Related protein 1 (CDR1) locus in an Ago2-slicer-dependent manner.
    Title: miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Other Names

  • cerebellar degeneration related protein 1
  • cerebellar degeneration-related antigen 1
  • cerebellar degeneration-related protein 1, 34kDa

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    140772083..140793212 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_006652813.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    139089454..139110579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_007091041.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_016361.1: Suppressed sequence

    Description
    NG_016361.1: This RefSeq was removed by NCBI staff.

  2. NM_004065.2: Suppressed sequence

    Description
    NM_004065.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51861.2 GenPept UniProtKB/Swiss-Prot:P51861

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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