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Paupar Pax6 upstream antisense RNA [ Mus musculus (house mouse) ]

Gene ID: 103164605, updated on 11-Mar-2024

Summary

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Official Symbol
Pauparprovided by MGI
Official Full Name
Pax6 upstream antisense RNAprovided by MGI
Primary source
MGI:MGI:5543919
See related
Ensembl:ENSMUSG00000102424 AllianceGenome:MGI:5543919
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables chromatin binding activity. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within neural precursor cell proliferation and neurogenesis. Is active in cytoplasm and nucleoplasm. Orthologous to human PAUPAR (PAX6 upstream antisense RNA). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human all
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Genomic context

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See Paupar in Genome Data Viewer
Location:
2 E3; 2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (105488207..105491688, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (105657862..105661343, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene paired box 6 opposite strand 1 Neighboring gene ribosomal protein L10, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_05312 Neighboring gene predicted gene, 35946 Neighboring gene Pax6 upstream regulatory region Neighboring gene STARR-seq mESC enhancer starr_05314 Neighboring gene enhancer in intron 4 of Pax6 Neighboring gene enhancer region in intron 7 of Pax6 Neighboring gene paired box 6 Neighboring gene elongator acetyltransferase complex subunit 4 Neighboring gene STARR-seq mESC enhancer starr_05317 Neighboring gene Pax6 downstream regulatory region Neighboring gene RB enhancer downstream of Pax6 Neighboring gene STARR-seq mESC enhancer starr_05318 Neighboring gene STARR-seq mESC enhancer starr_05319 Neighboring gene STARR-positive B cell enhancer ABC_E639 Neighboring gene IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Singer RA, et al. Cell Metab, 2019 Dec 3. PMID 31607563, Free PMC Article
  2. The long non-coding RNA Paupar regulates the expression of both local and distal genes. Vance KW, et al. EMBO J, 2014 Feb 18. PMID 24488179, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within_positive_effect gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within_negative_effect gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within_positive_effect gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic S phase IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neurogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_117095.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    KJ434993
    Related
    ENSMUST00000194826.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    105488207..105491688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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