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ZFPM2-AS1 ZFPM2 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 102723356, updated on 10-Oct-2023

Summary

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Official Symbol
ZFPM2-AS1provided by HGNC
Official Full Name
ZFPM2 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:50698
See related
AllianceGenome:HGNC:50698
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SCAT3
Expression
Low expression observed in reference dataset See more
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Genomic context

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See ZFPM2-AS1 in Genome Data Viewer
Location:
8q23.1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (105780410..106060503, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (106907977..107188448, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (106792638..107072731, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene zinc finger protein, FOG family member 2 Neighboring gene uncharacterized LOC105375696 Neighboring gene VISTA enhancer hs1800 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:106725429-106725978 Neighboring gene ribosomal protein L12 pseudogene 24 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:106814445-106815644 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:106898552-106899078 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:106965782-106966981 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:107072226-107073425 Neighboring gene uncharacterized LOC124902003 Neighboring gene Sharpr-MPRA regulatory region 12229 Neighboring gene solute carrier family 16 member 14 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. ZFPM2-AS1: An Oncogenic Long Non-coding RNA in Multiple Cancer Types. Tan F. Mini Rev Med Chem, 2023. PMID 35578882
  2. Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers. Sasa GBK, et al. Mol Biotechnol, 2022 Jul. PMID 35098483
  3. STAT1-induced regulation of lncRNA ZFPM2-AS1 predicts poor prognosis and contributes to hepatocellular carcinoma progression via the miR-653/GOLM1 axis. Zhang XW, et al. Cell Death Dis, 2021 Jan 4. PMID 33414427, Free PMC Article
  4. ZFPM2-AS1 facilitates cell proliferation and migration in cutaneous malignant melanoma through modulating miR-650/NOTCH1 signaling. Liu W, et al. Dermatol Ther, 2021 Mar. PMID 33406278
  5. Long noncoding RNA ZFPM2-AS1 acts as a miRNA sponge and promotes cell invasion through regulation of miR-139/GDF10 in hepatocellular carcinoma. He H, et al. J Exp Clin Cancer Res, 2020 Aug 14. PMID 32795316, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ZFPM2-AS1: An Oncogenic Long Non-coding RNA in Multiple Cancer Types.
    Title: ZFPM2-AS1: An Oncogenic Long Non-coding RNA in Multiple Cancer Types.
  2. Genome stabilityrelated lncRNA ZFPM2AS1 promotes tumor progression via miR30655p/XRCC4 in hepatocellular carcinoma.
    Title: Genome stability‑related lncRNA ZFPM2‑AS1 promotes tumor progression via miR‑3065‑5p/XRCC4 in hepatocellular carcinoma.
  3. LncRNA ZFPM2-AS1 Enhances Retinoblastoma Development by Targeting the miR-3612/NT5E Signaling Axis.
    Title: LncRNA ZFPM2-AS1 Enhances Retinoblastoma Development by Targeting the miR-3612/NT5E Signaling Axis.
  4. Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers.
    Title: Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers.
  5. Long noncoding RNA ZFPM2-AS1 regulates renal cell carcinoma progression via miR-130a-3p/ESCO2.
    Title: Long noncoding RNA ZFPM2-AS1 regulates renal cell carcinoma progression via miR-130a-3p/ESCO2.
  6. lncRNA ZFPM2-AS1 promotes retinoblastoma progression by targeting microRNA miR-511-3p/paired box protein 6 (PAX6) axis.
    Title: lncRNA ZFPM2-AS1 promotes retinoblastoma progression by targeting microRNA miR-511-3p/paired box protein 6 (PAX6) axis.
  7. SP1-induced lncRNA ZFPM2 antisense RNA 1 (ZFPM2-AS1) aggravates glioma progression via the miR-515-5p/Superoxide dismutase 2 (SOD2) axis.
    Title: SP1-induced lncRNA ZFPM2 antisense RNA 1 (ZFPM2-AS1) aggravates glioma progression via the miR-515-5p/Superoxide dismutase 2 (SOD2) axis.
  8. STAT1-induced regulation of lncRNA ZFPM2-AS1 predicts poor prognosis and contributes to hepatocellular carcinoma progression via the miR-653/GOLM1 axis.
    Title: STAT1-induced regulation of lncRNA ZFPM2-AS1 predicts poor prognosis and contributes to hepatocellular carcinoma progression via the miR-653/GOLM1 axis.
  9. LncRNA ZFPM2-AS1 aggravates the malignant development of breast cancer via upregulating JMJD6.
    Title: LncRNA ZFPM2-AS1 aggravates the malignant development of breast cancer via upregulating JMJD6.
  10. ZFPM2-AS1 facilitates cell proliferation and migration in cutaneous malignant melanoma through modulating miR-650/NOTCH1 signaling.
    Title: ZFPM2-AS1 facilitates cell proliferation and migration in cutaneous malignant melanoma through modulating miR-650/NOTCH1 signaling.
Submit: New GeneRIF Correction See all GeneRIFs (17)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • S-phase cancer-associated transcript 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_125796.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC090802, AP005362

  2. NR_125797.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks four alternate internal exons and contains an alternate internal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC090802, AC106856, AP005362

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    105780410..106060503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    106907977..107188448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases