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Gm12610 predicted gene 12610 [ Mus musculus (house mouse) ]

Gene ID: 102633081, updated on 16-Apr-2024

Summary

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Official Symbol
Gm12610provided by MGI
Official Full Name
predicted gene 12610provided by MGI
Primary source
MGI:MGI:3652143
See related
Ensembl:ENSMUSG00000086035 AllianceGenome:MGI:3652143
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ANRIL; Gm12609; LncR-APDC
Annotation information
Annotation category: suggests misassembly
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
4 C4; 4 42.15 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (89213417..89406858)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (89295180..89518621)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10736 Neighboring gene TGFB-induced factor homeobox 2, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_10737 Neighboring gene STARR-positive B cell enhancer ABC_E1646 Neighboring gene STARR-seq mESC enhancer starr_10738 Neighboring gene cyclin dependent kinase inhibitor 2A Neighboring gene STARR-positive B cell enhancer ABC_E11246 Neighboring gene STARR-seq mESC enhancer starr_10739 Neighboring gene STARR-seq mESC enhancer starr_10740 Neighboring gene cyclin dependent kinase inhibitor 2B Neighboring gene VISTA enhancer mm10 Neighboring gene STARR-seq mESC enhancer starr_10741 Neighboring gene heat shock protein 1 (chaperonin) pseudogene 8 Neighboring gene predicted gene, 54238 Neighboring gene STARR-seq mESC enhancer starr_10742 Neighboring gene STARR-seq mESC enhancer starr_10743 Neighboring gene predicted gene, 54239 Neighboring gene doublesex and mab-3 related transcription factor like family A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS. Wan J, et al. J Gene Med, 2023 Feb. PMID 36346049
  2. ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy. Sooshtari P, et al. PLoS One, 2022. PMID 35984863, Free PMC Article
  3. Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo. Deng L, et al. Neurol Res, 2021 Sep. PMID 34080525
  4. Long noncoding RNA-antisense noncoding RNA in the INK4 locus accelerates wound healing in diabetes by promoting lymphangiogenesis via regulating miR-181a/Prox1 axis. He ZY, et al. J Cell Physiol, 2019 Apr. PMID 30565672
  5. ANRIL regulates production of extracellular matrix proteins and vasoactive factors in diabetic complications. Thomas AA, et al. Am J Physiol Endocrinol Metab, 2018 Mar 1. PMID 29118015

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CDKN2B-AS1 mediates proliferation and migration of vascular smooth muscle cells induced by insulin.
    Title: CDKN2B-AS1 mediates proliferation and migration of vascular smooth muscle cells induced by insulin.
  2. Long non-coding RNA APDC plays important regulatory roles in metabolism of bone and adipose tissues.
    Title: Long non-coding RNA APDC plays important regulatory roles in metabolism of bone and adipose tissues.
  3. lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS.
    Title: lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS.
  4. ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy.
    Title: ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy.
  5. LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
    Title: LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
  6. Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-kappaB Pathway.
    Title: Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
  7. Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-kappaB in vitro and in vivo.
    Title: Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
  8. Mechanism of lncRNA-ANRIL/miR-181b in autophagy of cardiomyocytes in mice with uremia by targeting ATG5.
    Title: Mechanism of lncRNA-ANRIL/miR-181b in autophagy of cardiomyocytes in mice with uremia by targeting ATG5.
  9. Overexpression of long non-coding RNA ANRIL promotes post-ischaemic angiogenesis and improves cardiac functions by targeting Akt.
    Title: Overexpression of long non-coding RNA ANRIL promotes post-ischaemic angiogenesis and improves cardiac functions by targeting Akt.
  10. LncRNA ANRIL knockdown relieves myocardial cell apoptosis in acute myocardial infarction by regulating IL-33/ST2.
    Title: LncRNA ANRIL knockdown relieves myocardial cell apoptosis in acute myocardial infarction by regulating IL-33/ST2.
Submit: New GeneRIF Correction See all GeneRIFs (12)

General gene information

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Other Names

  • lncRNA APDC

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_132431.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK148321, AL844161, BX649611
    Related
    ENSMUST00000240726.1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    89213417..89406858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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