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RASSF1-AS1 RASSF1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 102060282, updated on 10-Oct-2023

Summary

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Official Symbol
RASSF1-AS1provided by HGNC
Official Full Name
RASSF1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:49091
See related
Ensembl:ENSG00000281358 AllianceGenome:HGNC:49091
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ANRASSF1
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Genomic context

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Location:
3p21.31
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (50337511..50338300)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (50367234..50368024)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (50374942..50375731)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:50357211-50357884 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14391 Neighboring gene hyaluronidase 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19900 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:50359913-50360586 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:50361369-50361870 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14392 Neighboring gene tumor suppressor 2, mitochondrial calcium regulator Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19901 Neighboring gene Ras association domain family member 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14393 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14394 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:50374977-50375548 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19903 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr3:50377372-50378195 and GRCh37_chr3:50378196-50379018 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:50380164-50380746 Neighboring gene zinc finger MYND-type containing 10 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:50382474-50383024 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:50383025-50383575 Neighboring gene NPR2 like, GATOR1 complex subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The long non-coding RNA ANRASSF1 in the regulation of alternative protein-coding transcripts RASSF1A and RASSF1C in human breast cancer cells: implications to epigenetic therapy. Calanca N, et al. Epigenetics, 2019 Aug. PMID 31062660, Free PMC Article
  2. ANRIL and ANRASSF1 long noncoding RNAs are upregulated in gastric cancer. Kangarlouei R, et al. J Cell Biochem, 2019 Aug. PMID 30834580
  3. The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation. Beckedorff FC, et al. PLoS Genet, 2013. PMID 23990798, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ANRIL and ANRASSF1 long noncoding RNAs are upregulated in gastric cancer.
    Title: ANRIL and ANRASSF1 long noncoding RNAs are upregulated in gastric cancer.
  2. Results found ANRASSF1 expression levels increased in breast cancer cell lines (BCC).
    Title: The long non-coding RNA ANRASSF1 in the regulation of alternative protein-coding transcripts RASSF1A and RASSF1C in human breast cancer cells: implications to epigenetic therapy.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_109831.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC002481
    Related
    ENST00000629828.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    50337511..50338300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    50367234..50368024
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases