U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ADAMTS9-AS1 ADAMTS9 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 101929335, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Official Symbol
ADAMTS9-AS1provided by HGNC
Official Full Name
ADAMTS9 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:40625
See related
Ensembl:ENSG00000241158 AllianceGenome:HGNC:40625
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in kidney (RPKM 21.7), ovary (RPKM 6.4) and 6 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ADAMTS9-AS1 in Genome Data Viewer
Location:
3p14.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (64561346..64590084)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (64604983..64633731)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (64547022..64575760)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377123 Neighboring gene PRICKLE2 divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:64474389-64475332 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:64475333-64476276 Neighboring gene MPRA-validated peak4681 silencer Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:64493024-64494223 Neighboring gene RNA, U6 small nuclear 739, pseudogene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:64526487-64527686 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 9 Neighboring gene NANOG hESC enhancer GRCh37_chr3:64582623-64583210 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:64627975-64628476 Neighboring gene NANOG hESC enhancer GRCh37_chr3:64663850-64664351 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:64670743-64671244 Neighboring gene ADAMTS9 antisense RNA 2 Neighboring gene uncharacterized LOC105377124 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:64930462-64931334 Neighboring gene MPRA-validated peak4685 silencer Neighboring gene uncharacterized LOC124909390

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. LncRNA ADAMTS9-AS1 knockdown suppresses cell proliferation and migration in glioma through downregulating Wnt/β-catenin signaling pathway. Zhou C, et al. Bosn J Basic Med Sci, 2022 Jun 1. PMID 34923953, Free PMC Article
  2. Long non-coding RNA ADAMTS9-AS1 suppresses colorectal cancer by inhibiting the Wnt/β-catenin signalling pathway and is a potential diagnostic biomarker. Li N, et al. J Cell Mol Med, 2020 Oct. PMID 32889785, Free PMC Article
  3. LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. Wang H, et al. Sci Rep, 2016 Dec 12. PMID 27941916, Free PMC Article
  4. The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy. Song B, et al. Biomed Res, 2023. PMID 37258203
  5. LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis. Wang P, et al. Genomics, 2023 May. PMID 36870548

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ADAMTS9-AS1 Long Non-coding RNA Sponges miR-128 and miR-150 to Regulate Ras/MAPK Signaling Pathway in Glioma.
    Title: ADAMTS9-AS1 Long Non‑coding RNA Sponges miR‑128 and miR-150 to Regulate Ras/MAPK Signaling Pathway in Glioma.
  2. The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy.
    Title: The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy.
  3. LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis.
    Title: LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis.
  4. LncRNA ADAMTS9-AS1 knockdown suppresses cell proliferation and migration in glioma through downregulating Wnt/beta-catenin signaling pathway.
    Title: LncRNA ADAMTS9-AS1 knockdown suppresses cell proliferation and migration in glioma through downregulating Wnt/β-catenin signaling pathway.
  5. Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by Targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer.
    Title: Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by Targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer.
  6. lncRNA ADAMTS9-AS1/circFN1 Competitively Binds to miR-206 to Elevate the Expression of ACTB, Thus Inducing Hypertrophic Cardiomyopathy.
    Title: lncRNA ADAMTS9-AS1/circFN1 Competitively Binds to miR-206 to Elevate the Expression of ACTB, Thus Inducing Hypertrophic Cardiomyopathy.
  7. Long non-coding RNA ADAMTS9-AS1 inhibits the progression of prostate cancer by modulating the miR-142-5p/CCND1 axis.
    Title: Long non-coding RNA ADAMTS9-AS1 inhibits the progression of prostate cancer by modulating the miR-142-5p/CCND1 axis.
  8. Long non-coding RNA ADAMTS9-AS1 suppresses colorectal cancer by inhibiting the Wnt/beta-catenin signalling pathway and is a potential diagnostic biomarker.
    Title: Long non-coding RNA ADAMTS9-AS1 suppresses colorectal cancer by inhibiting the Wnt/β-catenin signalling pathway and is a potential diagnostic biomarker.
Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

Go to the top of the page Help

Other Names

  • ADAMTS9 antisense RNA 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110150.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC096888, AC122178, DA222486
    Related
    ENST00000594810.3

  2. NR_110151.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon which results in a shorter transcript compared to variant 1.
    Source sequence(s)
    AC096888, AC122178, AK125532

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    64561346..64590084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    64604983..64633731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases