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LIPC-AS1 LIPC antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 101928694, updated on 10-Oct-2023

Summary

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Official Symbol
LIPC-AS1provided by HGNC
Official Full Name
LIPC antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:52294
See related
Ensembl:ENSG00000259293 AllianceGenome:HGNC:52294
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
15q21.3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (58434901..58498735, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (56236889..56300710, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (58727100..58790934, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6478 Neighboring gene uncharacterized LOC124903499 Neighboring gene ribosomal protein L28 pseudogene 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:58540501-58541001 Neighboring gene Sharpr-MPRA regulatory region 5540 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr15:58576109-58577308 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:58624073-58625272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:58638163-58638664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:58638665-58639164 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9466 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9467 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9468 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:58655345-58655845 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9469 Neighboring gene MPRA-validated peak2354 silencer Neighboring gene Sharpr-MPRA regulatory region 6038 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9470 Neighboring gene Sharpr-MPRA regulatory region 12189 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:58731214-58731454 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:58741275-58741775 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6479 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9471 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9472 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6480 Neighboring gene lipase C, hepatic type Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:58813484-58814683 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:58840709-58841347 Neighboring gene NANOG hESC enhancer GRCh37_chr15:58853387-58853916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9473 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9474 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9475 Neighboring gene small nucleolar RNA U13 Neighboring gene ADAM metallopeptidase domain 10 Neighboring gene high mobility group box 1 pseudogene 51

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. van Es MA, et al. Nat Genet, 2008 Jan. PMID 18084291
  2. Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. Wu Y, et al. J Lipid Res, 2013 Nov. PMID 24023260, Free PMC Article
  3. A genome-wide assessment of variability in human serum metabolism. Hong MG, et al. Hum Mutat, 2013 Mar. PMID 23281178
  4. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Waterworth DM, et al. Arterioscler Thromb Vasc Biol, 2010 Nov. PMID 20864672, Free PMC Article
  5. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Sherva R, et al. Alzheimers Dement, 2014 Jan. PMID 23535033, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide assessment of variability in human serum metabolism.
EBI GWAS Catalog
An atlas of genetic influences on human blood metabolites.
EBI GWAS Catalog
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
EBI GWAS Catalog
Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
EBI GWAS Catalog
Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.
EBI GWAS Catalog
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_120338.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC018904, AC084781
    Related
    ENST00000561083.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    58434901..58498735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    56236889..56300710 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials