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ZNF256 zinc finger protein 256 [ Homo sapiens (human) ]

Gene ID: 10172, updated on 10-Dec-2024

Summary

Official Symbol
ZNF256provided by HGNC
Official Full Name
zinc finger protein 256provided by HGNC
Primary source
HGNC:HGNC:13049
See related
Ensembl:ENSG00000152454 MIM:606956; AllianceGenome:HGNC:13049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BMZF3; BMZF-3
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in bone marrow (RPKM 4.0), testis (RPKM 3.0) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF256 in Genome Data Viewer
Location:
19q13.43
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (57940833..57947706, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (61037758..61044631, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58452201..58459074, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 417 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15169 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:58428025-58428880 Neighboring gene zinc finger protein 418 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58446173-58447055 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15173 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15174 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:58466320-58466487 Neighboring gene ribosomal protein L19 pseudogene 19 Neighboring gene chromosome 19 open reading frame 18

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in nucleoplasm  
is_active_in nucleus  
located_in nucleus PubMed 

General protein information

Preferred Names
zinc finger protein 256
Names
bone marrow zinc finger 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001375403.1NP_001362332.1  zinc finger protein 256 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010326
    Conserved Domains (2) summary
    COG5048
    Location:140473
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:368388
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_005773.3NP_005764.2  zinc finger protein 256 isoform 1

    See identical proteins and their annotated locations for NP_005764.2

    Status: VALIDATED

    Source sequence(s)
    AC010326
    Consensus CDS
    CCDS12966.1
    UniProtKB/Swiss-Prot
    B2RA92, Q53Y85, Q9BV71, Q9Y2P7
    Related
    ENSP00000282308.2, ENST00000282308.4
    Conserved Domains (3) summary
    COG5048
    Location:293626
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:521541
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1454
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    57940833..57947706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    61037758..61044631 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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