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NAMA non-protein coding RNA, associated with MAP kinase pathway and growth arrest [ Homo sapiens (human) ]

Gene ID: 100996569, updated on 10-Oct-2023

Summary

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Official Symbol
NAMAprovided by HGNC
Official Full Name
non-protein coding RNA, associated with MAP kinase pathway and growth arrestprovided by HGNC
Primary source
HGNC:HGNC:42408
See related
Ensembl:ENSG00000271086 MIM:620412; AllianceGenome:HGNC:42408
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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See NAMA in Genome Data Viewer
Location:
9q22.33
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (99355340..99375257, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (111526995..111546881, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (102117622..102137539, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 225 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20127 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28707 Neighboring gene uncharacterized LOC124902231 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:102068645-102069144 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28708 Neighboring gene keratin 8 pseudogene 11 Neighboring gene uncharacterized LOC124902232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28709 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:102131371-102131952 Neighboring gene uncharacterized LOC107987011 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr9:102181342-102182541 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:102195429-102196628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28712 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28713 Neighboring gene uncharacterized LOC124902236 Neighboring gene uncharacterized LOC124902233

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest. Yoon H, et al. Int J Cancer, 2007 Aug 15. PMID 17415708
  2. BRAF-Activated Long Noncoding RNA Modulates Papillary Thyroid Carcinoma Cell Proliferation through Regulating Thyroid Stimulating Hormone Receptor. Zheng H, et al. Cancer Res Treat, 2016 Apr. PMID 26323637, Free PMC Article
  3. Genetics of callous-unemotional behavior in children. Viding E, et al. PLoS One, 2013. PMID 23874384, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genetics of callous-unemotional behavior in children.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_102270.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    DQ673922, DQ673923, DQ673925, DQ673929, DQ673950, DQ673963
    Related
    ENST00000604258.5

  2. NR_102271.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks four internal exons, compared to variant 1.
    Source sequence(s)
    DQ673923, DQ673929, DQ673950, DQ673963

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    99355340..99375257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    111526995..111546881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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