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FRMD6-AS2 FRMD6 antisense RNA 2 [ Homo sapiens (human) ]

Gene ID: 100874185, updated on 10-Oct-2023

Summary

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Official Symbol
FRMD6-AS2provided by HGNC
Official Full Name
FRMD6 antisense RNA 2provided by HGNC
Primary source
HGNC:HGNC:43637
See related
Ensembl:ENSG00000258537 AllianceGenome:HGNC:43637
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in endometrium (RPKM 4.6), prostate (RPKM 0.5) and 1 other tissue See more
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Genomic context

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See FRMD6-AS2 in Genome Data Viewer
Location:
14q22.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (51454512..51599952, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (45661343..45806846, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (51921230..52066670, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:51861840-51862340 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:51862502-51863701 Neighboring gene long intergenic non-protein coding RNA 2310 Neighboring gene FERM domain containing 6 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:51934347-51935061 Neighboring gene SET pseudogene 2 Neighboring gene RNA, U6 small nuclear 1291, pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr14:52000910-52002109 Neighboring gene uncharacterized LOC124903415 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8374 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:52117631-52118249 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5737 Neighboring gene FRMD6 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The tumor suppressive effect of long non-coding RNA FRMD6-AS2 in uteri corpus endometrial carcinoma. Wang J, et al. Life Sci, 2020 Feb 15. PMID 31917993
  2. Voxelwise genome-wide association study (vGWAS). Stein JL, et al. Neuroimage, 2010 Nov 15. PMID 20171287, Free PMC Article
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Voxelwise genome-wide association study (vGWAS).
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • FRMD6 antisense RNA 2 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_047477.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AL122125
    Related
    ENST00000557625.1

  2. NR_051990.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two 3' exons and contains an alternate 3' terminal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AL122125, AL358332
    Related
    ENST00000556617.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    51454512..51599952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    45661343..45806846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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