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SGO1-AS1 SGO1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 100874028, updated on 10-Oct-2023

Summary

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Official Symbol
SGO1-AS1provided by HGNC
Official Full Name
SGO1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:41081
See related
Ensembl:ENSG00000231304 AllianceGenome:HGNC:41081
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGOL1-AS1
Expression
Broad expression in testis (RPKM 4.1), bone marrow (RPKM 3.6) and 16 other tissues See more
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Genomic context

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See SGO1-AS1 in Genome Data Viewer
Location:
3p24.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (20174286..20186115)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (20178271..20190093)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (20215778..20227607)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr3.1018 Neighboring gene ribosomal protein L39 pseudogene 18 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:20081563-20082533 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19579 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19580 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19581 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19582 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_67745 Neighboring gene lysine acetyltransferase 2B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19583 Neighboring gene MPRA-validated peak4562 silencer Neighboring gene microRNA 3135a Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14135 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19584 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19585 Neighboring gene shugoshin 1 Neighboring gene RNY4 pseudogene 22 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14136 Neighboring gene RNA, U6 small nuclear 822, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Assessment of SGO1 and SGO1-AS1 contribution in breast cancer. Nasim N, et al. Hum Antibodies, 2019. PMID 31156154
  2. Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis. Huang D, et al. J Exp Clin Cancer Res, 2021 Oct 28. PMID 34706749, Free PMC Article
  3. Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci. Greenwood TA, et al. Biol Psychiatry, 2012 Aug 15. PMID 22365631, Free PMC Article
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long noncoding RNA SGO1-AS1 inactivates TGFbeta signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis.
    Title: Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • SGOL1 antisense RNA 1 (non-protein coding)

Clone Names

  • AC099057.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_132785.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    DA754007
    Related
    ENST00000441442.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    20174286..20186115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    20178271..20190093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_046723.1: Suppressed sequence

    Description
    NR_046723.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases