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MIR4797 microRNA 4797 [ Homo sapiens (human) ]

Gene ID: 100616216, updated on 10-Oct-2023

Summary

Official Symbol
MIR4797provided by HGNC
Official Full Name
microRNA 4797provided by HGNC
Primary source
HGNC:HGNC:41758
See related
Ensembl:ENSG00000265850 miRBase:MI0017444; AllianceGenome:HGNC:41758
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:
3q29
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (197293878..197293948, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (200015143..200015214, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (197020749..197020819, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 2091 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15080 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15081 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15082 Neighboring gene ribosomal protein SA pseudogene 30 Neighboring gene MELTF antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21107 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15083 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15084 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:196756444-196757080 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:196757081-196757717 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:196758105-196759304 Neighboring gene melanotransferrin Neighboring gene MPRA-validated peak4992 silencer Neighboring gene discs large MAGUK scaffold protein 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:196860144-196860342 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:196930580-196931118 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15086 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15087 Neighboring gene DLG1 antisense RNA 1 Neighboring gene uncharacterized LOC101926923

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039960.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC092937
    Related
    ENST00000577559.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    197293878..197293948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    200015143..200015214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)