TEN1-CDK3 TEN1-CDK3 readthrough (NMD candidate) [Homo sapiens (human)] - Gene

Summary

Official Symbol: TEN1-CDK3provided by HGNC
Official Full Name: TEN1-CDK3 readthrough (NMD candidate)provided by HGNC
Primary source: HGNC:HGNC:44420
See related: Ensembl:ENSG00000261408 AllianceGenome:HGNC:44420
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: TEN1; C17orf106; C17orf106-CDK3
Summary: This locus represents naturally occurring read-through transcription between the neighboring TEN1 telomerase capping complex subunit homolog (S. cerevisiae) and cyclin-dependent kinase 3 (CDK3) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Oct 2011]
Expression: Ubiquitous expression in skin (RPKM 7.8), small intestine (RPKM 7.7) and 25 other tissues See more
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Genomic context

Location:: 17q25.1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	17	NC_000017.11 (75979217..76005999)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	17	NC_060941.1 (76872346..76899135)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	17	NC_000017.10 (73975298..74002080)

Chromosome 17 - NC_000017.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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General gene information

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Markers

D17S1728E (e-PCR)
- UniSTS:153962

RH94374 (e-PCR)
- UniSTS:89255

Other Names

CST complex subunit TEN1
Protein telomeric pathways with STN1 homolog
TEN1-CDK3 readthrough (non-protein coding)
Telomere length regulation protein TEN1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.