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Mir1251 microRNA 1251 [ Mus musculus (house mouse) ]

Gene ID: 100526517, updated on 8-Feb-2024

Summary

Official Symbol
Mir1251provided by MGI
Official Full Name
microRNA 1251provided by MGI
Primary source
MGI:MGI:4834231
See related
Ensembl:ENSMUSG00000093227 miRBase:MI0014021; AllianceGenome:MGI:4834231
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mir-1251; mmu-mir-1251
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:
10 C2; 10 46.73 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (91973002..91973085, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (92137140..92137223, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31673 Neighboring gene microRNA 135a-2 Neighboring gene rhabdomyosarcoma 2 associated transcript (non-coding RNA) Neighboring gene predicted gene, 20757 Neighboring gene STARR-seq mESC enhancer starr_27558 Neighboring gene predicted gene 8512 Neighboring gene STARR-seq mESC enhancer starr_27559 Neighboring gene STARR-positive B cell enhancer mm9_chr10:91850807-91851108 Neighboring gene STARR-seq mESC enhancer starr_27560 Neighboring gene predicted gene, 40738

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037219.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC125204
    Related
    ENSMUST00000175486.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    91973002..91973085 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)