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LINC01605 long intergenic non-protein coding RNA 1605 [ Homo sapiens (human) ]

Gene ID: 100507420, updated on 10-Oct-2023

Summary

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Official Symbol
LINC01605provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1605provided by HGNC
Primary source
HGNC:HGNC:51654
See related
Ensembl:ENSG00000253414 AllianceGenome:HGNC:51654
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ODIR1; LincDUSP
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
8p11.23
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (37403516..37599839, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (37678855..37875158, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (37261034..37457357, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100507403 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:37188590-37189789 Neighboring gene uncharacterized LOC124901930 Neighboring gene VISTA enhancer hs302 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27225 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37310647-37311224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37374880-37375400 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37375401-37375919 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:37378682-37379881 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:37387319-37387531 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37400987-37401487 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37404685-37405219 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37405335-37405836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37405837-37406336 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37413320-37413920 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:37417549-37418050 Neighboring gene uncharacterized LOC105379379 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:37418051-37418550 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37438583-37439182 Neighboring gene uncharacterized LOC105379378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37439183-37439782 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:37452253-37453174 Neighboring gene uncharacterized LOC105379380 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37462486-37462996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37467873-37468422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37468423-37468972 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27227 Neighboring gene uncharacterized LOC124901931 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:37494669-37495193 Neighboring gene VISTA enhancer hs834 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:37496445-37496652 Neighboring gene RNA, U6 small nuclear 607, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer. Wang W, et al. Cancer Sci, 2022 Aug. PMID 35411612, Free PMC Article
  2. Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis. Forrest ME, et al. Sci Rep, 2018 May 9. PMID 29743621, Free PMC Article
  3. LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p. Wang XY, et al. Eur Rev Med Pharmacol Sci, 2019 Dec. PMID 31841192
  4. LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11. Hu SS, et al. Eur Rev Med Pharmacol Sci, 2021 Feb. PMID 33629302
  5. LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis. He S, et al. Cell Death Dis, 2019 Dec 11. PMID 31827076, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01605 Is a Novel Target of Mutant p53 in Breast and Ovarian Cancer Cell Lines.
    Title: LINC01605 Is a Novel Target of Mutant p53 in Breast and Ovarian Cancer Cell Lines.
  2. LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer.
    Title: LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer.
  3. LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11.
    Title: LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11.
  4. LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
    Title: LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
  5. key role of lincDUSP in the regulation of important pathways in colon cancer
    Title: Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • RP11-527N22.2
  • TCONS_00014973
  • osteogenic differentiation inhibitory regulator 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_121620.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  2. NR_121621.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124067
    Related
    ENST00000668286.1

  3. NR_170186.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  4. NR_170187.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124067

  5. NR_170188.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124067

  6. NR_170189.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  7. NR_170190.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  8. NR_170191.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  9. NR_170192.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  10. NR_170193.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

  11. NR_170194.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007590, AC091182, AC124067

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    37403516..37599839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    37678855..37875158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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