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LINC01013 long intergenic non-protein coding RNA 1013 [ Homo sapiens (human) ]

Gene ID: 100507254, updated on 25-Oct-2023

Summary

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Official Symbol
LINC01013provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1013provided by HGNC
Primary source
HGNC:HGNC:48987
See related
Ensembl:ENSG00000228495 AllianceGenome:HGNC:48987
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AERRIE; LINC02921
Expression
Biased expression in testis (RPKM 1.0), lymph node (RPKM 0.8) and 10 other tissues See more
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Genomic context

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See LINC01013 in Genome Data Viewer
Location:
6q23.2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (132132572..132169374)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (133327603..133364404)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (132455118..132490514)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene CCN2 antisense RNA 1 Neighboring gene cellular communication network factor 2 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:132324214-132325413 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25069 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:132453077-132454276 Neighboring gene microRNA 548aj-1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 36 Neighboring gene monooxygenase DBH like 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:132675510-132676709 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17547 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17548

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide. Quaife NM, et al. J Cardiovasc Transl Res, 2023 Feb. PMID 35759180, Free PMC Article
  2. Novel role of LINC01013/miR-6795-5p/FMNL3 axis in the regulation of hepatocellular carcinoma stem cell features. Wang W, et al. Acta Biochim Biophys Sin (Shanghai), 2021 May 21. PMID 33847733
  3. Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function. Pham TP, et al. Front Cell Dev Biol, 2020. PMID 33505972, Free PMC Article
  4. The long non-coding RNA LINC01013 enhances invasion of human anaplastic large-cell lymphoma. Chung IH, et al. Sci Rep, 2017 Mar 22. PMID 28331184, Free PMC Article
  5. Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve. Chignon A, et al. PLoS Genet, 2022 Jan. PMID 35041643, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide.
    Title: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide.
  2. Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve.
    Title: Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve.
  3. Novel role of LINC01013/miR-6795-5p/FMNL3 axis in the regulation of hepatocellular carcinoma stem cell features.
    Title: Novel role of LINC01013/miR-6795-5p/FMNL3 axis in the regulation of hepatocellular carcinoma stem cell features.
  4. Collectively, these findings support a potential role for LINC01013 in cancer cell invasion through the snail-fibronectin activation cascade.
    Title: The long non-coding RNA LINC01013 enhances invasion of human anaplastic large-cell lymphoma.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • Age and EndMT Regulated RNA In Endothelium
  • LINC01013ORF
  • long intergenic non-protein coding RNA 2921

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038981.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408
    Related
    ENST00000706359.1

  2. NR_146223.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  3. NR_187597.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408
    Related
    ENST00000669240.2

  4. NR_187598.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  5. NR_187599.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408
    Related
    ENST00000706315.1

  6. NR_187600.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  7. NR_187601.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  8. NR_187602.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  9. NR_187603.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408

  10. NR_187604.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL021408
    Related
    ENST00000654779.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    132132572..132169374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    133327603..133364404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials