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GPRC5D-AS1 GPRC5D and HEBP1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 100506314, updated on 10-Oct-2023

Summary

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Official Symbol
GPRC5D-AS1provided by HGNC
Official Full Name
GPRC5D and HEBP1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:53599
See related
Ensembl:ENSG00000247498 AllianceGenome:HGNC:53599
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 8.3), thyroid (RPKM 2.6) and 19 other tissues See more
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Genomic context

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Location:
12p13.1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (12927726..13022498)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (12801331..12896717)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (13080660..13175432)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902881 Neighboring gene RPL13AP20-GPRC5A intergenic CAGE-defined mid-level expression enhancer Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 12:13058787 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 12:13059781 Neighboring gene G protein-coupled receptor class C group 5 member A Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 12:13073965 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 12:13075202 Neighboring gene microRNA 614 Neighboring gene G protein-coupled receptor class C group 5 member D Neighboring gene small nucleolar RNA SNORD88 Neighboring gene heme binding protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4269 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4270 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4271 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13154718-13155263 Neighboring gene 5-hydroxytryptamine receptor 7 pseudogene 1 Neighboring gene ribosomal protein S26 pseudogene 46 Neighboring gene family with sequence similarity 234 member B Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:13237538-13238737 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13239727-13240549 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13240550-13241371 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13241372-13242194 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13242195-13243015 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:13243112-13243710 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4272 Neighboring gene uncharacterized LOC105369666 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4273 Neighboring gene germ cell associated 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk. Jin M, et al. Environ Mol Mutagen, 2017 Jul. PMID 28612367
  2. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Adams MD, et al. Nature, 1995 Sep 28. PMID 7566098
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Increased Expression of Long Noncoding RNA LOC100506314 in T cells from Patients with Nonsegmental Vitiligo and Its Contribution to Vitiligo Pathogenesis.
    Title: Increased Expression of Long Noncoding RNA LOC100506314 in T cells from Patients with Nonsegmental Vitiligo and Its Contribution to Vitiligo Pathogenesis.
  2. These findings indicate that rs10845671 may contribute to the susceptibility to colorectal cancer and be a candidate biomarker for colorectal cancer risk prediction.[RNA RP11-392P7.6]
    Title: Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038920.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK093401, BC042978
    Related
    ENST00000499948.2

  2. NR_149062.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA362711, AA412641, BC042978, BF976135

  3. NR_149063.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA412641, BF976135, BU684530, CR746233

  4. NR_149064.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA412641, BF976135, BQ951575, BU684530

  5. NR_149065.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007688, BF976135, BU684530

  6. NR_149066.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BF976135, BU684530, HY076286
    Related
    ENST00000543515.8

  7. NR_149067.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC023790, BF976135, DA768922

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    12927726..13022498
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    12801331..12896717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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