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Tincr TINCR ubiquitin domain containing [ Mus musculus (house mouse) ]

Gene ID: 100504425, updated on 2-May-2024

Summary

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Official Symbol
Tincrprovided by MGI
Official Full Name
TINCR ubiquitin domain containingprovided by MGI
Primary source
MGI:MGI:5012404
See related
Ensembl:ENSMUSG00000110218 AllianceGenome:MGI:5012404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm20219
Summary
This gene encodes a spliced long non-coding RNA. A similar gene in human is associated with epidermal tissue differentiation. [provided by RefSeq, Dec 2014]
Expression
Broad expression in stomach adult (RPKM 13.4), bladder adult (RPKM 9.6) and 22 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 D; 17 29.39 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (56858414..56861403, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56551414..56554387, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10963 Neighboring gene predicted gene, 33258 Neighboring gene zinc and ring finger 4 Neighboring gene scaffold attachment factor B2 Neighboring gene STARR-positive B cell enhancer ABC_E5623 Neighboring gene scaffold attachment factor B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A ubiquitin-like protein encoded by the "noncoding" RNA TINCR promotes keratinocyte proliferation and wound healing. Nita A, et al. PLoS Genet, 2021 Aug. PMID 34351912, Free PMC Article
  2. LncRNA Tincr regulates PKCɛ expression in a miR-31-5p-dependent manner in cardiomyocyte hypertrophy. Li H, et al. Naunyn Schmiedebergs Arch Pharmacol, 2020 Dec. PMID 32157348
  3. TINCR is not a non-coding RNA but encodes a protein component of cornified epidermal keratinocytes. Eckhart L, et al. Exp Dermatol, 2020 Apr. PMID 32012357, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A ubiquitin-like protein encoded by the ""noncoding"" RNA TINCR promotes keratinocyte proliferation and wound healing.
    Title: A ubiquitin-like protein encoded by the "noncoding" RNA TINCR promotes keratinocyte proliferation and wound healing.
  2. LncRNA Tincr regulates PKCvarepsilon expression in a miR-31-5p-dependent manner in cardiomyocyte hypertrophy.
    Title: LncRNA Tincr regulates PKCɛ expression in a miR-31-5p-dependent manner in cardiomyocyte hypertrophy.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

General protein information

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Preferred Names
TINCR ubiquitin domain containing
Names
tissue differentiation-inducing non-protein coding RNA-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396442.1 → NP_001383371.1  TINCR ubiquitin domain containing

    Status: VALIDATED

    Source sequence(s)
    CT485788
    UniProtKB/TrEMBL
    A0A1B0GRQ3
    Related
    ENSMUSP00000159834.1, ENSMUST00000249631.1
    Conserved Domains (1) summary
    cd17039
    Location:18 → 85
    Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins

  2. NM_001396443.1 → NP_001383372.1  TINCR ubiquitin domain containing

    Status: VALIDATED

    Source sequence(s)
    CT485788
    UniProtKB/TrEMBL
    A0A1B0GRQ3
    Conserved Domains (1) summary
    cd17039
    Location:18 → 85
    Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins

  3. NM_001396444.1 → NP_001383373.1  TINCR ubiquitin domain containing

    Status: VALIDATED

    Source sequence(s)
    CT485788
    UniProtKB/TrEMBL
    A0A1B0GRQ3
    Related
    ENSMUSP00000147618.2, ENSMUST00000209718.3
    Conserved Domains (1) summary
    cd17039
    Location:18 → 85
    Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    56858414..56861403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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