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Zfp534 zinc finger protein 534 [ Mus musculus (house mouse) ]

Gene ID: 100503584, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp534provided by MGI
Official Full Name
zinc finger protein 534provided by MGI
Primary source
MGI:MGI:3650650
See related
Ensembl:ENSMUSG00000062518 AllianceGenome:MGI:3650650
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13159
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
4 E1; 4 78.53 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147757964..147787088, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147674225..147702631, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12058 Neighboring gene zinc finger protein 985 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146958877-146959178 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146960015-146960316 Neighboring gene zinc finger protein 979 Neighboring gene high mobility group box 1-like pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr4:147051587-147051888 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147058330-147058631 Neighboring gene STARR-seq mESC enhancer starr_12059 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147083962-147084263 Neighboring gene STARR-seq mESC enhancer starr_12060 Neighboring gene predicted gene 13137 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  2. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  3. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 534
Names
novel KRAB box domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127188.2 → NP_001120660.1  zinc finger protein 534

    Status: VALIDATED

    Source sequence(s)
    AL606910, CF167429
    Consensus CDS
    CCDS57313.1
    UniProtKB/TrEMBL
    A2A7A1
    Related
    ENSMUSP00000113561.2, ENSMUST00000117638.2
    Conserved Domains (5) summary
    smart00349
    Location:13 → 55
    KRAB; krueppel associated box
    COG5048
    Location:226 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:338 → 363
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    147757964..147787088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163555.1 → XP_036019448.1  zinc finger protein 534 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:263 → 676
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:307 → 327
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:49 → 89
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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