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Tpbgl trophoblast glycoprotein-like [ Mus musculus (house mouse) ]

Gene ID: 100503386, updated on 8-Mar-2024

Summary

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Official Symbol
Tpbglprovided by MGI
Official Full Name
trophoblast glycoprotein-likeprovided by MGI
Primary source
MGI:MGI:3646425
See related
Ensembl:ENSMUSG00000096606 AllianceGenome:MGI:3646425
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm4980; EG245190
Summary
Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human TPBGL (trophoblast glycoprotein like). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human all
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Genomic context

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Location:
7 E1; 7 54.11 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99273274..99276310, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99624067..99627103, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19659 Neighboring gene predicted gene, 40450 Neighboring gene predicted gene, 34172 Neighboring gene arrestin, beta 1 Neighboring gene microRNA 326 Neighboring gene predicted gene, 53384 Neighboring gene predicted gene, 25409

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • 6430704N06

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
trophoblast glycoprotein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195529.1 → NP_001182458.1  trophoblast glycoprotein-like precursor

    See identical proteins and their annotated locations for NP_001182458.1

    Status: VALIDATED

    Source sequence(s)
    AC111086, AK032609
    Consensus CDS
    CCDS57566.1
    UniProtKB/Swiss-Prot
    Q8C013
    Related
    ENSMUSP00000137154.2, ENSMUST00000178124.3
    Conserved Domains (3) summary
    smart00082
    Location:236 → 288
    LRRCT; Leucine rich repeat C-terminal domain
    sd00031
    Location:98 → 121
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:96 → 153
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    99273274..99276310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C013.2 GenPept UniProtKB/Swiss-Prot:Q8C013

Gene LinkOut

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