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Zfp648 zinc finger protein 648 [ Mus musculus (house mouse) ]

Gene ID: 100503355, updated on 8-Mar-2024

Summary

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Official Symbol
Zfp648provided by MGI
Official Full Name
zinc finger protein 648provided by MGI
Primary source
MGI:MGI:2685049
See related
Ensembl:ENSMUSG00000066797 AllianceGenome:MGI:2685049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm203; Gm10178
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF648 (zinc finger protein 648). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 36.0) See more
Orthologs
human all
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Genomic context

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Location:
1 G3; 1 65.97 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (154076933..154088955)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (154201187..154213209)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30327 Neighboring gene RIKEN cDNA A830008E24 gene Neighboring gene STARR-seq mESC enhancer starr_02710 Neighboring gene predicted gene, 46165 Neighboring gene predicted gene, 25336 Neighboring gene STARR-seq mESC enhancer starr_02711 Neighboring gene STARR-seq mESC enhancer starr_02712 Neighboring gene STARR-seq mESC enhancer starr_02713 Neighboring gene predicted gene, 30388 Neighboring gene RIKEN cDNA 4930452N14 gene Neighboring gene RIKEN cDNA 4930532M18 gene Neighboring gene predicted gene, 30465

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  2. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 648

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204908.2 → NP_001191837.1  zinc finger protein 648

    See identical proteins and their annotated locations for NP_001191837.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AC118263
    Consensus CDS
    CCDS56646.1
    UniProtKB/TrEMBL
    D3Z0W3
    Related
    ENSMUSP00000083370.6, ENSMUST00000086195.7
    Conserved Domains (4) summary
    COG5048
    Location:262 → 508
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:238 → 258
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:489 → 511
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:420 → 444
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_166709.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC118263

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    154076933..154088955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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