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Rpl37rt ribosomal protein L37, retrotransposed [ Mus musculus (house mouse) ]

Gene ID: 100502825, updated on 8-Feb-2024

Summary

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Official Symbol
Rpl37rtprovided by MGI
Official Full Name
ribosomal protein L37, retrotransposedprovided by MGI
Primary source
MGI:MGI:3651519
See related
Ensembl:ENSMUSG00000121818 AllianceGenome:MGI:3651519
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpl37; Gm13826; EyeLinc4
Summary
Predicted to enable MDM2/MDM4 family protein binding activity and ubiquitin ligase inhibitor activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Predicted to act upstream of or within negative regulation of ubiquitin protein ligase activity. Predicted to be located in cytosolic ribosome. Orthologous to human RPL37 (ribosomal protein L37). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 408.1), CNS E11.5 (RPKM 382.4) and 28 other tissues See more
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Genomic context

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Location:
5 F; 5 55.99 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115240981..115248327, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115102922..115110268, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene HNF1 homeobox A Neighboring gene STARR-seq mESC enhancer starr_14093 Neighboring gene HNF1 homeobox A, opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_14096 Neighboring gene signal peptide peptidase 3 Neighboring gene STARR-seq mESC enhancer starr_14098 Neighboring gene STARR-seq mESC enhancer starr_14099 Neighboring gene predicted gene, 54336 Neighboring gene acyl-Coenzyme A dehydrogenase, short chain Neighboring gene STARR-positive B cell enhancer ABC_E10342 Neighboring gene unc-119 lipid binding chaperone B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Evolutionarily conserved long intergenic non-coding RNAs in the eye. Mustafi D, et al. Hum Mol Genet, 2013 Aug 1. PMID 23562822, Free PMC Article
  2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables MDM2/MDM4 family protein binding ISO
Inferred from Sequence Orthology
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables growth factor binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
enables ubiquitin ligase inhibitor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in positive regulation of signal transduction by p53 class mediator ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL37
Names
60S ribosomal protein L37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271590.1 → NP_001258519.1  large ribosomal subunit protein eL37

    See identical proteins and their annotated locations for NP_001258519.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC119205
    UniProtKB/Swiss-Prot
    Q6ZWV1, Q9D823
    Related
    ENSMUST00000100847.5
    Conserved Domains (1) summary
    PTZ00073
    Location:1 → 88
    PTZ00073; 60S ribosomal protein L37; Provisional

  2. NM_001271591.1 → NP_001258520.1  large ribosomal subunit protein eL37

    See identical proteins and their annotated locations for NP_001258520.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC119205, BB707379
    UniProtKB/Swiss-Prot
    Q6ZWV1, Q9D823
    Conserved Domains (1) summary
    PTZ00073
    Location:1 → 88
    PTZ00073; 60S ribosomal protein L37; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    115240981..115248327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D823.3 GenPept UniProtKB/Swiss-Prot:Q9D823

Gene LinkOut

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