U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LINC00674 long intergenic non-protein coding RNA 674 [ Homo sapiens (human) ]

Gene ID: 100499466, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Official Symbol
LINC00674provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 674provided by HGNC
Primary source
HGNC:HGNC:44355
See related
AllianceGenome:HGNC:44355
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CALA
Expression
Ubiquitous expression in thyroid (RPKM 7.9), brain (RPKM 7.3) and 25 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
17q24.2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (68101555..68135929)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (68978345..69012721)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (66097696..66132070)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66031597-66032144 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12635 Neighboring gene MPRA-validated peak2956 silencer Neighboring gene karyopherin subunit alpha 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66076452-66076952 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66076953-66077453 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66083143-66083718 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12636 Neighboring gene uncharacterized LOC124904048 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66097037-66097816 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66097817-66098595 Neighboring gene F-box protein 36 pseudogene 1 Neighboring gene leucine rich repeat containing 37 member A16, pseudogene Neighboring gene SH3 domain containing GRB2 like 1, endophilin A2 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66150047-66150548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66150549-66151048 Neighboring gene uncharacterized LOC105371870 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66165711-66166210 Neighboring gene RDM1 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12637 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12639 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66180501-66181101 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12640 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12641

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hypoxia-induced LINC00674 facilitates hepatocellular carcinoma progression by activating the NOX1/mTOR signaling pathway. Zhu N, et al. J Cancer, 2022. PMID 36118523, Free PMC Article
  2. The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. Kirchhof L, et al. Noncoding RNA, 2022 Jun 30. PMID 35893232, Free PMC Article
  3. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

Go to the top of the page Help

Markers

Other Names

  • cytoplasmic G3BP1-associated lncRNA

Clone Names

  • FLJ33831, FLJ35479

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027418.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005332, AC145343, BC045718, DA232946

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    68101555..68135929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    68978345..69012721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Miscellaneous