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Spmip2 sperm microtubule inner protein 2 [ Mus musculus (house mouse) ]

Gene ID: 100233207, updated on 8-Mar-2024

Summary

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Official Symbol
Spmip2provided by MGI
Official Full Name
sperm microtubule inner protein 2provided by MGI
Primary source
MGI:MGI:4936993
See related
Ensembl:ENSMUSG00000091685 AllianceGenome:MGI:4936993
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm17359
Summary
Is expressed in testis. Orthologous to human C4orf45 (chromosome 4 open reading frame 45). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 87.6) See more
Orthologs
human all
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Genomic context

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Location:
3 E3; 3 34.91 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (79243937..79371436)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (79336630..79464129)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor (GEF) 2 Neighboring gene RIKEN cDNA 6430573P05 gene Neighboring gene STARR-seq mESC enhancer starr_07995 Neighboring gene predicted gene, 40072 Neighboring gene STARR-seq mESC enhancer starr_07997 Neighboring gene STARR-seq mESC enhancer starr_07998 Neighboring gene STARR-seq mESC enhancer starr_07999 Neighboring gene STARR-seq mESC enhancer starr_08000 Neighboring gene folliculin interacting protein 2 Neighboring gene STARR-seq mESC enhancer starr_08002 Neighboring gene RIKEN cDNA 4930589L23 gene Neighboring gene STARR-seq mESC enhancer starr_08006 Neighboring gene peptidylprolyl isomerase D (cyclophilin D) Neighboring gene electron transferring flavoprotein, dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

General protein information

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Preferred Names
protein SPMIP2
Names
sperm associated microtubule inner protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142953.2 → NP_001136425.1  protein SPMIP2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC142502
    Consensus CDS
    CCDS50933.1
    UniProtKB/TrEMBL
    E9QAV2
    Related
    ENSMUSP00000130702.2, ENSMUST00000164216.6
    Conserved Domains (1) summary
    pfam15123
    Location:21 → 132
    DUF4562; Domain of unknown function (DUF4562)

  2. NM_001370773.1 → NP_001357702.1  protein SPMIP2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC142502
    Consensus CDS
    CCDS89638.1
    UniProtKB/TrEMBL
    A0A0G2JEB7
    Related
    ENSMUSP00000142709.2, ENSMUST00000199658.2
    Conserved Domains (1) summary
    pfam15123
    Location:21 → 117
    DUF4562; Domain of unknown function (DUF4562)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    79243937..79371436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252332.1 → XP_030108192.1  protein SPMIP2 isoform X1

  2. XM_011239979.2 → XP_011238281.1  protein SPMIP2 isoform X1

    See identical proteins and their annotated locations for XP_011238281.1

  3. XM_011239980.3 → XP_011238282.1  protein SPMIP2 isoform X1

    See identical proteins and their annotated locations for XP_011238282.1

Nucleotide Protein
Heading Accession and Version

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