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ADIRF-AS1 ADIRF antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 100133190, updated on 10-Oct-2023

Summary

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Official Symbol
ADIRF-AS1provided by HGNC
Official Full Name
ADIRF antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:45127
See related
AllianceGenome:HGNC:45127
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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Genomic context

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Location:
10q23.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (86965287..86971240, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (87849000..87854949, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (88725044..88730997, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor type 1A Neighboring gene RNA, U1 small nuclear 19, pseudogene Neighboring gene Sharpr-MPRA regulatory region 4131 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3698 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88700126-88700626 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88704401-88704974 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88713843-88714442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88715044-88715643 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88718646-88719245 Neighboring gene multimerin 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88720446-88721046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88721647-88722246 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3699 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3700 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88726172-88726925 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88726926-88727678 Neighboring gene Sharpr-MPRA regulatory region 6517 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:88730527-88731726 Neighboring gene uncharacterized LOC124902474 Neighboring gene synuclein gamma Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 Neighboring gene adipogenesis regulatory factor Neighboring gene BMS1 pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis. Zhong H, et al. Transl Res, 2022 Jul. PMID 35196590
  2. Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761. Xu L, et al. Bioengineered, 2022 Feb. PMID 35030964, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761.
    Title: Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Markers

Clone Names

  • DKFZp434C185

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_170177.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  2. NR_170178.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  3. NR_170179.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  4. NR_170180.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  5. NR_170181.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  6. NR_170182.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  7. NR_170183.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  8. NR_170184.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

  9. NR_170185.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC025268, AL136982

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    86965287..86971240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    87849000..87854949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials