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Esp8 exocrine gland secreted peptide 8 [ Mus musculus (house mouse) ]

Gene ID: 100126778, updated on 11-Apr-2024

Summary

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Official Symbol
Esp8provided by MGI
Official Full Name
exocrine gland secreted peptide 8provided by MGI
Primary source
MGI:MGI:4937129
See related
Ensembl:ENSMUSG00000090747 AllianceGenome:MGI:4937129
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm17495
Summary
Enables pheromone activity. Located in extracellular space. Is expressed in embryo and eye. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
17 B2; 17 19.53 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (40830913..40841593)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (40520022..40530702)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42541 Neighboring gene solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 pseudogene Neighboring gene solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_42542 Neighboring gene STARR-seq mESC enhancer starr_42543 Neighboring gene STARR-seq mESC enhancer starr_42544 Neighboring gene predicted gene, 29748 Neighboring gene predicted gene, 46573

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss-of-function mutations in FREM2 disrupt eye morphogenesis. Zhang X, et al. Exp Eye Res, 2019 Apr. PMID 30802441
  2. The roles of gene duplication, gene conversion and positive selection in rodent Esp and Mup pheromone gene families with comparison to the Abp family. Karn RC, et al. PLoS One, 2012. PMID 23094077, Free PMC Article
  3. Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Kimoto H, et al. Curr Biol, 2007 Nov 6. PMID 17935991

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables pheromone activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pheromone activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within signal transduction ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
exocrine gland-secreting peptide 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177584.1 → NP_001171055.1  exocrine gland-secreting peptide 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC161605
    Consensus CDS
    CCDS57092.1
    UniProtKB/TrEMBL
    A8R0U1, F7AMQ8
    Related
    ENSMUSP00000129933.3, ENSMUST00000171813.4
    Conserved Domains (1) summary
    pfam16590
    Location:29 → 85
    ESP; Exocrine gland-secreting peptide

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    40830913..40841593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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